Fig. 2
From: A retro-inverso cell-penetrating peptide for siRNA delivery
Characterization of RICK:siRNA nanoparticles. a Pre-formed RICK:siRNA and CADY-K:siRNA complexes were analyzed by electrophoresis on agarose gel (1% wt/vol) stained with GelRed. Data represent: mean ± SD, with n = 3. b Intrinsic tryptophan fluorescence emission spectra of RICK and CADY-K in 5% glucose and in the presence of siRNA at a peptide:siRNA molar ratio of R = 20. c, d Environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM) images of RICK:siRNA nanoparticles in ultra-pure water at a peptide/siRNA molar ratio of R = 20. Scales bars correspond to 5 µm and 500 nm for ESEM and TEM, respectively