Fig. 5
From: A retro-inverso cell-penetrating peptide for siRNA delivery
Cellular evaluation of RICK:siRNA nanoparticles. a Relative Luc activity (%FLuc/%RLuc) and relative toxicity (LDH quantification) after transfection with RICK-, CADY-K- and d-cady-k-based complexes in U87-FLuc-RLuc cells. siFLuc and siSCR correspond to siRNA anti-firefly Luciferase and its scrambled version, respectively. b Evaluation of RICK:siLuc and CADY-K:siLuc inhibiting efficiency after different PBN storage duration. Relative Luc activity (%FLuc/ %RLuc) was measured after PBN storage of 24, 48, 72 h, 1 week and 2 months. c Gene silencing on the endogenic protein cyclin B1. siSCR scrambled siRNA, N.T. non-treated cells, siCycB1 siRNA anti-Cyclin B1, Vincu. Vinculine