Fig. 6
From: A retro-inverso cell-penetrating peptide for siRNA delivery
Evaluation of nanoparticles in the presence of trypsin or serum. a Relative Luc activity (%FLuc/%RLuc) after transfection with RICK- and CADY-K-based nanoparticles in U87-FLuc-RLuc cells after pre-incubation with trypsin. siFLuc and siSCR correspond to siRNA anti-firefly Luciferase and its scrambled version, respectively. b Evaluation of RICK:siCycB1 and CADY-K:siCycB1 inhibiting efficiency after transfection in the presence of medium with 10% serum. c Evaluation of RICK:siCycB1 and CADY-K:siCycB1 inhibiting efficiency after pre-incubation of nanoparticles 2 h in 10% serum at 37 °C before transfection. siSCR scrambled siRNA, N.T. non-treated cells, siCycB1 siRNA anti-Cyclin B1