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Table 2 Zeta potential (ZP) of RICK, CADY-K and d-cady-k

From: A retro-inverso cell-penetrating peptide for siRNA delivery

ID

ZP (mV)

5% glucosea

OptiMEM

DMEM

RICK

40 ± 2

14 ± 3

14 ± 1

CADY-K

38 ± 1

13 ± 1

12 ± 3

d-Cady-k

40 ± 1

n.d.

n.d.

  1. All CPP:siRNA complexes were formed at R = 20 using a siRNA concentration of 500 nM in an aqueous solution of 5% glucose, OptiMEM or DMEM
  2. a For zeta potential (ZP) assessment the solution was supplemented with 5 mM NaCl (OptiMEM and DMEM contained NaCl)