Fig. 8
From: Uptake of label-free graphene oxide by Caco-2 cells is dependent on the cell differentiation status
TEM analysis of the interaction of GO and differentiated Caco-2 cells. TEM images of differentiated Caco-2 cells grown on permeable supports: A, B control cells without GO exposure, C Caco-2 cells after exposure to 20 µg/ml GO1 for 24 h. D–F Caco-2 cell morphology after exposure to 20 µg/ml GO3 for 24 h (E polarized cell layer on PC membrane. D, F Microvilli-arrangement). Neither GO1 nor GO3 sheets could be found closely attached to or internalized by differentiated Caco-2 cells