Table 1 Sequences and intended use of synthetic oligodeoxynucleotides
Type | Sequence | Intended use and remarks |
|---|---|---|
CS-ODN | 5′-ACG CTG CCG CCA CCA CAC CA-3′ | Adsorbed to pristine and modified MWCNT |
NH2-CS-ODN | 5′-NH2-C6-ACG CTG CCG CCA CCA CAC CA-3′ | Covalently bound to EDC/NHS-activated MWCNT-COOH; following activation with DSS covalently bound to MWCNT-NH2 |
Mal-CS-ODN | 5′-Mal-ACG CTG CCG CCA CCA CAC CA-3′ | Covalently bound to MWCNT-SH |
AS-ODN | 5′-TGG TGT GGT GGC GGC AGC GT-3′ | Therapeutic AS-ODN against the angiogenic growth factor VEGF, complementary to CS-ODN |
NS-ODN | 5′-CCA AAC CCG TCA ATC AAG TC-3′ | Control, non-complementary to CS-ODN |