Fig. 8

Therapeutic efficacy of DNS-[C6&DC]m in glioma-bearing mice. A Schematic illustration of the administration regimenfor DNS-[C6&DC]m therapy. B MRI of normal and glioma-bearing mice after different treatments. C H&E staining of the tumor tissues. D Immunohistochemical staining of CD31 and Caspase-3 (E) of the tumors. F TUNEL staining analysis of the tumors (×40 magnification). G Quantification using ImageJ of TUNEL apopotosis after different administration (**p < 0.01, ***p < 0.001, ns, not significant). H Kaplan–Meier survival curve of glioma-bearing mice after drug treatment. I Body weight changes of mice in different treatment groups