Fig. 2

CFH/OM-L reverses CAFs activation and EMT in vitro. Immunofluorescence staining of A α-SMA, B vimentin, C N-cadherin and D E-cadherin after TGF-β1-activated LX-2 cells were treated with various formulations. Scale bar: 20 μm. Representative images of western blot depicting bands for E N-cadherin, vimentin, F snail and G E-cadherin in various formulation groups. Quantification of H N-cadherin, I vimentin, J snail and K E-cadherin expression after treatments with different formulations. Data are represented as mean ± SD, n = 3. Compared with the normal group, ^#P < 0.05; compared with the PBS group, *P < 0.05, **P < 0.01