Fig. 2

Bone-targeting ability of PL-exo-ALN. A Frequency shifts of exosomes deposition on the HAp coated sensor were detected by QCM-D. B Fluorescent Image of DiD-labelled exosomes binding to HAp were detected by IVIS. C Quantitative analysis of DiD-labelled exosomes binding to HAp by a fluorescence microplate reader. D Fluorescent Image of the in vivo distribution of DiD-labelled exosomes by IVIS. E Internalization of exosomes into BMSCs (scale bar: 10 μm). All results are presented as the means ± SDs, ^*P < 0.05, ^**P < 0.01