Fig. 8

KP-SeNPs have in vivo anticancer effects. KP-SeNPs and 5-FU were administered to AGS xenograft mice (n = 5) for 16 days. A Volume of tumor tissues isolated from xenograft-bearing mice. B Tumor weight and size in AGS xenograft-bearing mice. C Body weights of the xenograft-bearing mice. D Weight indices of the liver and kidneys. E IHC staining of LC3 and caspase 3 in tumor tissues isolated from AGS xenograft-bearing mice. F Hematoxylin and eosin Y staining of the liver and kidneys of mice from each group. *p < 0.05, **p < 0.01, and ***p < 0.001 compared with Con-T. Abbreviations: Con: Control; Con-T: Con-tumor; KP-SeNP-5: 5 mg/kg of KP-SeNPs; KP-SeNP-10: 10 mg/kg of KP-SeNPs; 5-FU-5: 5 mg/kg of 5-FU