Fig. 5

HAOPTs suppressed the polarization of M2 macrophages and tumor cell invasion in vitro. A Flow cytometry analysis of CD206 on macrophages in different treatment groups. B Images of invasive tumor cells stained by crystal violet in matrigel invasion assay. Scale bar, 100 µm. C Quantitative analysis of tumor cell invasion. Data were represented as mean ± SD (n = 3), *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001