Fig. 12

Effect of EPO-PLGA-PEG on axon morphology and myelinated fibers. A Representative transverse sciatic nerve immunofluorescent images of nuclei (DAPI), NF-H, and MPZ sectioned at the level of injury on day 21. B Quantification of percent myelinated fibers (n = 5/group; mean ± SEM; ^**p < 0.01 and ^***p < 0.001 vs. saline group; ^σp < 0.05 and ^σσσp < 0.001 vs. PLGA-PEG group; ^#p < 0.05 and ^###p < 0.001 vs. uninjured group; scale bar = 10 μm). Each image represents 3 images from 5 different SNs, for a total of 15 images analyzed per group