Fig. 6From: Uterine macrophages as treatment targets for therapy of premature rupture of membranes by modified ADSC-EVs through a circRNA/miRNA/NF-κB pathwayTherapeutic efficacies of different F4/80-EVs in PROM mice. A Representative fluorescence imaging of various F4/80-EVs (1 × 109 particles/mouse) in whole-body and organ tissues from PROM mice. B Relative fluorescence intensity in the uterus, kidneys, liver, and spleen of PROM mice (n = 3). C Analysis of PROM timing after various F4/80-EV treatments in the PROM mouse model (n = 5). D–F ELISA of MMP-9, MMP-2, and MMP-13 expression in amniotic fluid derived from normal control and PROM model mice (n = 3); ns, not significant; *p < 0.05; **p < 0.01; ***p < 0.001Back to article page