Fig. 10From: Tenofovir-tethered gold nanoparticles as a novel multifunctional long-acting anti-HIV therapy to overcome deficient drug delivery-: an in vivo proof of conceptLight photomicrograph of histopathology of the major organs collected from the healthy BALB/c mice treated with 5Â mg/kg of AuNPs at two-time points. (Magnification 40X for all images, except heart images taken at 10X magnification) Light micrographs of the organ sections from the different treatment groups. The letters on the images represent the treatment groups. A, B, C, D, and E No abnormality was detected in the control group. Control kidney section showing normal renal cortex and glomerular tufts, relatively healthy glomerulus with abundant capsular space. F, G, H, I, and J No abnormality was detected 48Â h post-injection. K, L No abnormality detected, M Minimal focal peri-glomerular edema (arrow) observed in the kidney. N Minimal congestion of blood vessels (arrow) detected in the lung. O No abnormality was detectedBack to article page