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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Tea leaf-derived exosome-like nanotherapeutics retard breast tumor growth by pro-apoptosis and microbiota modulation

Fig. 5

Transcriptome analysis of tumors from various mouse groups. A Volcano plot of differentially expressed genes (DEGs) between the control group and the LTNT (i.v., high)-treated group. B Volcano plot of DEGs between the control group and the LTNT (oral, high)-treated group. C Venn diagram showing overlapped genes among the control group, the LTNT (i.v., high)-treated group and the LTNT (oral, high)-treated group. D Heatmap showing significantly up-regulated and down-regulated genes in the tumors from mouse groups receiving various treatments (fold change ≥ 2 and p < 0.05). E Gene Ontology (GO) enrichment analysis for genes in the brown module. The color represents the adjusted p-values, and the sizes of the spots represent the gene numbers. (F) KEGG pathway analysis for cell apoptosis-associated genes (n = 3)

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