Fig. 7

In vivo biosafety evaluation of TLNTs after i.v. injection and oral administration. A Body weight variations, B organ indices, C pro-inflammatory cytokine levels of various mouse groups. The concentrations of D Complement C3, E ALT, F AST, G BUN and H CRE in plasma from mice receiving the treatment of TLNTs via i.v. and oral routes. Each point represents the mean ± S.E.M. (n = 3; *p < 0.05, **p < 0.01 and ***p < 0.001)