Fig. 3
Dual mitoDNA damage properties of CS-HAP@ATO NPs. A CLSM images of Ca2+ (green) in CT26 cells (left), and the statistic green intensity (right). Scale bar: 100 μm. B mPTP images of CT26 cells (left), and the statistic green intensity (right). Scale bar: 100 μm. C MitoSOX images of CT26 cells (left), and the statistic red intensity (right). Scale bar: 100 μm. D Flow cytometry images of JC-1 in CT26 cells (left), and the statistic results of JC-1 (right). E OX-MitoDNA (8-OHdG) images of CT26 cells (left), and the statistic red intensity (right). Scale bar: 100 μm. n = 3. *P < 0.05, **P < 0.01, ***P < 0.001