Fig. 5

Histopathological assessment on kidney function and anti-apoptotic efficacy. A Schematic illustration depicting the establishment of AKI mouse models and the subsequent therapeutic regimen. B CRE, C BUN, D CK, E LDH, F AST, G ALT, H ALP, I UP levels in AKI mice at 24 h after treatment with RES, PUA NPs and PUA NPs@RES (n = 5). J Representative histological H and E and apoptosis (TUNEL) staining images of renal tissues collected from different treatment groups. Scale bar: 100 μm