Fig. 3

Microfluidic technology for oocytes. a Denuded oocytes were obtained by stripping cumulus cells in a microfluidic chip [140]. Copyright 2018 Royal Society of Chemistry. b Oocyte culture on a microfluidic chip. By utilizing multi-channel microfluidic chips and designing new microcolumns, which can now achieve reliable and consistent capture of viable oocytes and facilitate dynamic cell culture. [141]. Copyright 2020 Springer Nature. c A simple microfluidic method for separating high-quality oocytes from poor-quality ones based on the differential deposition rate in sucrose buffer [143]. Copyright 2018 Springer Nature. d The on-chip robots driven by the permanent magnet in microfluidic chip achieve the operation of oocytes [152]. Copyright 2011 Royal Society of Chemistry. e A micro-robot was used to achieve enucleation in the closed space of the microfluidic chip [157]. Copyright 2013 MDPI. f On-chip three-dimensional cell rotation method based on the vibration-induced flow [160]. Copyright 2015 Springer Nature