Revolutionizing the female reproductive system research using microfluidic chip platform

Table 1 Comparisons among various microfluidic chips designed for different parts of the female reproductive system

Microfluidic chip type	Application field	Reproductive organs	Compatibility with downstream analysis	Issues of note	Advantages
Diagnosis	STD testing, HPV screening	Cervix uteri and vagina	High	Limited specificity and sensitivity	Easy integration with portable devices
Fertility testing	Ovulation monitoring, Fertility health	Ovary	Low	Variations of menstrual cycle	Synchronization with patient's menstrual cycle required
IVF assistance	Oocyte capture, embryo culture	Fallopian tube	Low	Necessity to mimic the natural reproductive environment	Precise environmental control
Drug screening	Drug response assessment	All	High	Simulation of drug metabolism and physiological responses	High-throughput analysis
Disease modeling	Endometriosis, polycystic ovary syndrome cancer	All	High	Complexity in reproducing disease characteristics	High-fidelity tissue engineering
Self-management	Menstrual cycle tracking	Uterus and vagina	Low	User-friendliness and data privacy	Synchronization with smart devices
Detection	Hormone level monitoring	Ovary	High	Long-term stability and reliability	Micro-sample processing

STD Sexually transmitted diseases; HPV Human papillomavirus; IVF In-vitro fertilization

ISSN: 1477-3155