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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Bioactive VS4-based sonosensitizer for robust chemodynamic, sonodynamic and osteogenic therapy of infected bone defects

Fig. 5

Treatment of infectious bone defect and verification of material functions. SD rats was put to death after 28 days of treatment, and a Reconstructed 3D images (first row), single-layer CT images (second row) and 3D picture of VOI (third row) processed from Micro-CT data. b Masson staining (first row) and Safranine O-Fast Green staining (second row) of samples; c quantitative analysis of new bone BV/TV. d, e SD rats on day 7 after surgery for WBCs and nGRANs test. f HE staining (first row) and Giemsa staining (second row) of bone samples. n = 3 independent experiments per group, *P < 0.05, **P < 0.01, ***P < 0.001, n.s. stands for not significant

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