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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Long-acting anti-inflammatory injectable DEX-Gel with sustained release and self-healing properties regulates TH1/TH2 immune balance for minimally invasive treatment of allergic rhinitis

Fig. 7

DEX-Gel regulates the expression of inflammatory factors in NALF as well as GATA-3 and T-bet in histopathological tissues. A–F Total IgE, OVA-Specific IgE, IL4, IL5, IL13, and IFN-γ levels in the NALF were quantified by ELISA (n = 3). G Representative IHC images of the GATA-3+ cells. Arrows point to nuclear-stained GATA-3+ cells. H Representative IHC images of the T-bet+ cells. Arrows point to nuclear-stained T-bet+ cells. Scale bars = 2.5 mm on the left side of (G, H); Scale bars = 50 µm on the right side of (G, H). Data are expressed as mean ± SD. *P < 0.05, **P < 0.01 and ***P < 0.001, significantly different from the ANOVA group

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