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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Calcium phosphate coating enhances osteointegration of melt electrowritten scaffold by regulating macrophage polarization

Fig. 5

Mechanistic analysis of CaP-PCL induced macrophage polarization. A, B Volcano plot and heatmap of differently expressed genes of macrophages cultured on PCL and CaP-PCL scaffolds. C GO analysis of PCL versus CaP-PCL samples. D KEGG analysis of PCL in comparison with CaP-PCL samples. E The protein expressions of key markers in cAMP signaling pathway. F The protein expressions of key markers in PI3K-Akt signaling pathway. G Scheme illustration of the mechanism of CaP-PCL induced macrophage polarization. n = 3

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