Fig. 6

Evaluation of the macrophage polarization in a subcutaneous implantation model. A–C Immunofluorescent images of sections in different groups after subcutaneous implantation for 1, 2 and 4 weeks: red (M0 marker: CD68), green (M1 marker: iNOS and M2 marker: CD206). D, E Immunochemistry images of sections in different groups after subcutaneous implantation for 4 weeks. F, G The proportion of iNOS/CD68 and CD206/CD68 positive cells at different groups from 1 to 4 weeks. H, I The proportion of IL-6 and IL-10 positive cells after subcutaneous implantation for 4 weeks. n = 9. **P < 0.01, ***P < 0.001 and ****P < 0.0001