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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Two-dimensional nanomaterials induced nano-bio interfacial effects and biomedical applications in cancer treatment

Fig. 7

2D NMs as PDT agents. A Schematic illustration of the defect engineering of CoMo-LDH nanosheets, surface modification with PEG and its application in NIR-III PDT. B The fluorescence intensity of SOSG in presence of the CoMo-LDH and DR-CoMo-LDH nanosheets in H2O under 1567 nm laser irradiation (0.5 W cm.−2). C In vitro cytotoxicity profiles of 4T1 cells incubated with DR-CoMo-LDH-PEG under different conditions. D Tumor growth curves of mice after various treatments. E Representative photographs of mice with treatments at various time points. F corresponding average weight of tumors taken on Day 16. (Reproduced with permission from Ref. [177], Copyright 2022, Springer Nature) G Schematic illustration of semiconducting 2D H-silicene nanosheets of selective biodegradability for in the photodynamic tumor-specific therapy. H Confocal fluorescence images of 4T1 cells treated with DCFH-DA after different treatments. I Relative viabilities of 4T1 cells after incubated with varied concentrations of H-silicene nanosheets with or without 660 nm irradiation. J Tumor growth curves of 4T1 tumor model received different treatments. K H&E and TUNEL for 4T1 tumor tissues in mice models after different treatments in day 21. (Reproduced with permission from Ref. [179], Copyright 2021, Elsevier)

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