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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Injectable ultrasound-powered bone-adhesive nanocomposite hydrogel for electrically accelerated irregular bone defect healing

Fig. 7

Transcriptome analysis of BMSCs gene expression in different groups. (a) PCA analysis of all data of GO, 0.1KBGO, and 0.1KBGO + US groups. (b) Pearson correlation coefficient heatmap of all samples. (c) Venn diagram of the number of differentially expressed genes among GO, 0.1KBGO, and 0.1KBGO + US groups. (d-f) Volcano analysis of differentially expressed genes of 0.1KBGO + US vs. GO, 0.1KBGO + US vs. 0.1KBGO, and 0.1KBGO vs. GO. (g-h) The top 20 significant up-enriched GO terms of 0.1KBGO + US vs. GO and 0.1KBGO + US vs. 0.1KBGO. (i-j) The top 20 significant up-enriched KEGG pathways of 0.1KBGO + US vs. GO and 0.1KBGO + US vs. 0.1KBGO. (k) Heatmap of the represented up-regulated genes in GO, 0.1KBGO, and 0.1KBGO + US. n = 3 biological replicates per group

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