Fig. 6
Long-lasting inhibition of bacterial cystitis by intravesical injection of Lev@PADM. A–C Bacterial colony counts in urine, bladder, and kidney following treatment with saline (up-left), Levofloxacin (up-right), PADM (down-right), and Lev@PADM (down-left) in a bacterial cystitis model. D Time-dependent changes in levofloxacin concentration in mouse urine after a single administration. E Fluorescence co-localization of E. coli and UPKIII in the bladder tissue on the 7th day post-treatment. (*p < 0.05; **p < 0.01; ***p < 0.001. Scale bar: 50 μm. Red arrows indicate positively stained cells with intracellular bacteria)