Fig. 8
The mechanism of the 3D-printed scaffolds on macrophage reprogramming. A, B The volcano map and hot map of RAW264.7 cultured in control and SGCM groups showing the different gene expression. C GO enrichment between control and SGCM groups (red circles represent immune-related processes green circles represent migration-related processes). D Hot map of DEGs about immune and inflammation. E KEGG pathway gene enrichment analysis. F, G mRNA expression of Smad 6 and Smad 7 which involved in TGF-β pathway. H Schematic illustration of the mechanisms of SGCM on macrophage reprogramming. *P < 0.05, **P < 0.01 or.***P < 0.001