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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: A novel extracellular vesicles production system harnessing matrix homeostasis and macrophage reprogramming mitigates osteoarthritis

Fig. 7

miRNA sequencing and bioinformatics analysis. (A) Heatmap illustrating differentially expressed miRNAs between NC-sEVs and EMF-USPIO-sEVs. (B) Scatter plot depicting the expression profile and global distribution of 28 differentially expressed miRNAs between NC-sEVs and EMF-USPIO-sEVs. (C) KEGG pathway enrichment analysis reveals several signaling pathways associated with OA progression. (D) Volcano plot highlights mRNAs exhibiting a ≥ 2-fold differential expression between NC-sEVs and EMF-USPIO-sEVs. Green represents downregulated mRNAs, while red denotes upregulated ones. (E) GO enrichment analysis of differentially expressed miRNAs

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Journal of Nanobiotechnology

ISSN: 1477-3155

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