Fig. 8

In vivo NIR-triggered photothermal-enhanced catalytic therapy of MCF7 xenograft tumor-bearing BALB/c nude mice. A Schematic illustration of the therapeutic protocol. B, G Digital photographs of the dissected tumors. The relative tumor volumes of MCF7 tumor-bearing mice treated with various C Tli08105 and H Tli10209-based treatments through i.v. modes. Tumor weights of each group after NIR-triggered locoregional D arginine and I asparagine deprivation-photothermal therapy. Body weight curves of nude mice during E Tli08105- and J Tli10209-photothermal synergistic therapy. F, K H&E, Ki67 and TUNEL staining of the tumor tissues harvested from corresponding mice after various treatments. The scale bars are (H&E) 100 μm, and (Ki67, TUNEL) 50 μm, respectively