Fig. 6
From: M2 microglia-derived exosomes promote vascular remodeling in diabetic retinopathy
Effect of exosomes from M2 microglia on hRECs. A The uptake of hRECs into exosomes was detected by labeling them with Dil. Scale bar = 20 μm. B Tube formation ability was measured. Migration of hRECs was determined by Transwell assay. Scale bar = 200 μm. C, D Proliferation of hRECs was assessed by the EdU assay. The percentage of EdU-positive cells (marked in red) was calculated using three randomly selected regions. Scale bar = 20 μm. E, F Immunofluorescence detection and quantification of ZO-1 in hRECs. Scale bar = 20 μm. G The morphology of vascular TJs in each group of mice was observed by TEM (arrows represent TJs). Scale bar = 2 μm