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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Exosomes secreted by Fusobacterium nucleatum-infected colon cancer cells transmit resistance to oxaliplatin and 5-FU by delivering hsa_circ_0004085

Fig. 9

Fn infection promoted hsa_circ_0004085 formation by hnRNP L and packaged hsa_circ_0004085 into exosomes by hnRNP A1. Exosomes secreted by Fusobacterium nucleatum-infected colon cancer deliver hsa_circ_0004085 between cells. Hsa_circ_0004085 delivered in this way relieves ER stress in recipient cells by regulating GRP78 and ATF6p50, thereby delivering resistance to oxaliplatin and 5-FU

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Journal of Nanobiotechnology

ISSN: 1477-3155

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