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Fig. 11 | Journal of Nanobiotechnology

Fig. 11

From: Apoptotic extracellular vesicles derived from hypoxia-preconditioned mesenchymal stem cells within a modified gelatine hydrogel promote osteochondral regeneration by enhancing stem cell activity and regulating immunity

Fig. 11

Evaluation of cartilage regeneration in vivo. A H&E, safranin O-fast green, toluidine blue, COL II immunohistochemical and Sirius red staining of repaired cartilage in the different groups after 6 and 12 weeks. B MODHS histological evaluations of repaired cartilage (n = 3). C Modifed O 'Driscoll scores were used for histological evaluation of cartilage repair after 6 and 12 weeks of knee joint in rats.D Quantitative analysis of COL II expression was also performed. Statistical analysis: *p < 0.05, **p < 0.01, ***p < 0.001. ns indicates no significant difference

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