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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Apoptotic extracellular vesicles derived from hypoxia-preconditioned mesenchymal stem cells within a modified gelatine hydrogel promote osteochondral regeneration by enhancing stem cell activity and regulating immunity

Fig. 3

Effects of different ApoEVs on the migration and proliferation of BMSCs. A Representative immunofluorescence images of EdU staining. B Quantitative analysis of the EdU (+) cell ratio. C CCK-8 results showing BMSC proliferation after treatment with different ApoEVs. D Flow cytometry results showing the cell cycle distribution of BMSCs treated with different ApoEVs. E Representative images of the different groups at 0 h, 12 h, and 24 h in the wound healing experiment. F Quantitative analysis of the wound healing distance in the different groups. G Structural diagram of the Transwell chambers. H Representative images of Transwell experiments. I Quantitative analysis of migrated cells in different groups. Statistical analysis: *p < 0.05, **p < 0.01, ***p < 0.001. ns indicates no significant difference, n = 3

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