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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Apoptotic extracellular vesicles derived from hypoxia-preconditioned mesenchymal stem cells within a modified gelatine hydrogel promote osteochondral regeneration by enhancing stem cell activity and regulating immunity

Fig. 4

Evaluation of the chondrogenic differentiation of BMSCs treated with the different ApoEVs. A Representative images of SOX9, Acan and COL II immunofluorescence staining and Alcian blue staining in BMSCs treated with different ApoEVs. B H&E, toluidine blue and safranin-O staining and immunohistochemical staining for collagen II in BMSC pellets that were incubated with different ApoEVs. C Quantitative analysis of immunofluorescence staining of SOX9, Acan and COL II in BMSCs. D qPCR analysis of the expression of hyaline cartilage (SOX9, Acan and COL II)/fibrocartilage (COL I) markers in BMSCs cultured with different ApoEVs

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