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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: M2 macrophage-derived exosomal miR-26b-5p regulates macrophage polarization and chondrocyte hypertrophy by targeting TLR3 and COL10A1 to alleviate osteoarthritis

Fig. 2

Exosomal miRNA expression profiles and bioinformatic analysis. A Hierarchical clustering showing a distinguishable miRNA between M1- and M2-derived exosomes. Volcano plot (B) and scatter plot (C) of differentially expressed exosomal miRNA. D Differentially expressed miRNA was verified via qRT-PCR, and mRNA fold-change was normalized to U6. E KEGG pathways of the differentially expressed miRNA. F Identified target genes of miR-26b-5p. *p < 0.05, **p < 0.01

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