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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: M2 macrophage-derived exosomal miR-26b-5p regulates macrophage polarization and chondrocyte hypertrophy by targeting TLR3 and COL10A1 to alleviate osteoarthritis

Fig. 4

miR-26b-5p orchestrate macrophages polarization. M1/M2 macrophage marker CD16/32 (A) and CD206 (B) were assessed by immunostaining. C The effect of miR-26b-5p on the morphology of macrophages. D The percentage of M1 and M2 macrophages were assessed by flow cytometry. E Quantitative analysis of M1/M2 macrophages percentage. F Effects of miR-26b-5p om M1 macrophages related genes including IL-1β, IL-6, TNF-α, PTGS2, and iNOS/Arg-1 measured by qRT-PCR. *p < 0.05, **p < 0.01, NS means not significant

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