Fig. 4
From: NIR-IIb fluorescence antiangiogenesis copper nano-reaper for enhanced synergistic cancer therapy
In vivo antitumor effect on PC-3 tumor loaded nude mouse model. (A) Schematic illustration of the therapeutic process in vivo (B) Tumor volume growth curves of five treatment groups in nude mice during the monitoring period. (C) Photographs of PC-3 tumors obtained from the nude mice after different treatments for 11 days. (D) Corresponding PC-3 tumor weight in the different treatment groups after 11 days (*P < 0.05, **P < 0.01, ***P < 0.001). (E) Body weight variation of nude mice after various treatments during the monitoring period. (Fi) Tumor tissue vessel fluorescence imaging of FITC using CLSM. (Fii) CD31, HSP70, VEGFA expression and H&E staining analysis of PC-3 tumor tissues after the various treatments