Fig. 3
Co-culture Study of M@BPICT with BMSCs. A Fluorescence images of BMSCs treated with Cy5.5-modified BPICT and Cy5.5-modified M@BPICT for different times. (blue: DAPI, red: CY5.5, scale bars: 50 μm). B Live/Dead and C CCK-8 analysis of BMSCs cultured with various materials for 24, 72, and 120 h. (Green: live cells, Red: dead cells). NIR irradiation: 808 nm, 1.0 W cm−2, 10 min per 24 h. Scale bars: 200 μm. D Cell scratch assay and E quantitative analysis of migration area after BMSCs co-cultured with ICT or M@BPICT for 24 h. Scale bars: 200 μm. [BPAvi: 565.4 μg L−1, BPICT: 1486.4 μg L−1, M@BPICT: at the same BPICT concentration of 1486.4 μg L−1, calculated by 1 μM ICT. All statistical data are represented as mean ± SD (n = 6; ns P > 0.05; ***P < 0.001)]