Fig. 8
Effect of YSA-SPION-MV/MTX on OS-mediated bone destruction and lung metastasis. Representative A X-ray and B micro-CT images of right hindlimbs from tumor-bearing mice in control, YSA-SPION-MV, MTX, MV/MTX and YSA-SPION-MV/MTX group (The dose was equivalent to 5Â mg/kg MTX) (scale bars: 5Â mm and 1Â mm). Representative H&E staining images of (C) right hindlimbs and (D) lung from tumor-bearing mice in different groups (scale bars: 1Â mm and 2Â mm)