Fig. 4From: Kilogram scale facile synthesis and systematic characterization of a Gd-macrochelate as T1-weighted magnetic resonance imaging contrast agentEvaluation of the efficacy and safety of Gd-HPMA12 on mice. A, B: T1-weighted MR images and the corresponding pseudo-color images of 4T1 tumor-bearing mice after intravenous injection of Gd-HPMA12 (CGd = 5.0 mg/kg) at different time intervals observed by a 3.0 T MRI scanner. C: ΔSNR for the MRI images A, B of tumors from 4T1 tumor-bearing mice post-injection of Gd-HPMA12 at different time intervals. Gd dosage = 5.0 mg/kg. Mean ± SD, n = 3Back to article page