Skip to main content
Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: A novel multifunctional microneedle patch for synergistic photothermal- gas therapy against maxillofacial malignant melanoma and associated skin defects

Fig. 3

The photothermal and NO releasing performances of SNP-Fe@MNs. a The heating curves of SNP-Fe@MNs loading loaded with 0.01, 0.03, 0.05, 0.10 and 0.15 g mL−1 SNP and Fe2+ under NIR irradiation at 1.0 W cm−2. b The heating curves of SNP-Fe@MNs loading 0.01, 0.03, 0.05, 0.10 and 0.15 g mL−1 SNP and Fe2+ under NIR irradiation at 1.5 W cm−2. c The heating curves of SNP-Fe@MNs loaded with 0.03 g mL−1 SNP and Fe2+ under varied power densities of NIR irradiation. d The cyclic heating curves of SNP-Fe@MNs loaded with 0.03 g mL−1 SNP and Fe2+ under NIR irradiation at 1.5 W cm−2. e The NO releasing curves of SNP-Fe@MNs loading 0.01, 0.03, 0.05, 0.10 and 0.15 g mL−1 SNP and Fe2+ under UV irradiation. f The NO releasing curves of SNP-Fe@MNs loading 0.01, 0.03, 0.05, 0.10 and 0.15 g mL−1 SNP and Fe2+ without UV irradiation. g The intracellular NO detected with 3-Amino, 4-Aminomethyl-2′,7′-difluorescein, diacetate (DAF-FM DA) fluorescence probe in B16 and HUVECs. h The intracellular fluorescence intensity of DAF-FM DA probe in B16 and HUVECs

Back to article page