Fig. 4
The anti-fibrotic efficiency of ChGelMSC−Exo on days 7 and 21. A–C The quantification of the IHC results on α-SMA, collagen-I, fibronectin, scale bars, 100 μm. D Immunofluorescence double staining for Collagen-I and α-SMA (yellow arrows indicate the myofibroblast cells). Scale bars, 100 μm. All data are shown as the means ± SEM. Statistical significance was analyzed by one-way ANOVA followed by a Tukey post hoc analysis among multiple groups, respectively. *P < 0.05, **P < 0.01. Pigs, n = 3 (day 7); n = 5 (day 21)