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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Hydralazine loaded nanodroplets combined with ultrasound-targeted microbubble destruction to induce pyroptosis for tumor treatment

Fig. 3

Biocompatibility, biodistribution and intracellular uptake. (A) Cellular uptake of Dil-marked HYD-NDs under varied pH settings. Scale bar: 100 μm. (B) Cellular uptake of HYD-NDs marked with Dil following ultrasonic irradiation. Scale bar: 100 μm. (C) Fluorescence images captured of isolated tumors and main organs at different time intervals. (D) NDs’ in vitro biocompatibility at different doses for a 24-hour treatment period. (E) In vitro hemolysis assay with different doses of NDs, using deionized water as a positive control. (F) The Dil-marked HYD-NDs accumulation curve in tumors and major organs was produced using Fig. C. All data are provided as means ± SD (n = 3)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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