Table 1 Cellular uptake of polymer coated MNP in SH-SY5Y, MCF-7 and U973 cells at 25 µgmL-1 over 72 h (n = 3 ± SD).
Particle | Incubation time h | Concentration of Fe3+ uptake per cell, pg (± SE) | ||
|---|---|---|---|---|
| Â | Â | SH-SY5Y | MCF-7 | U937 |
MNP-PEI | 0 | 0.560 (0.017) | 0.261 (0.004) | 0.121 (0.087) |
| Â | 1 | 16.205(0.867) | 7.990 (3.581) | 7.017 (0.377) |
| Â | 4 | 14.426 (0.577) | 14.257 (0.415) | 11.640 (0.405) |
| Â | 24 | 23.277 (0.506) | 16.167 (1.258) | 12.057 (1.315) |
| Â | 72 | 25.580 (0.353) | 19.847 (1.305) | 13.803 (1.842) |
MNP-PEI-PEG | 0 | 0.560 (0.017) | 0.261 (0.004) | 0.121 (0.087) |
| Â | 1 | 8.227 (0.523) | 7.027 (0.424) | 5.163 (0.484) |
| Â | 4 | 9.997 (0.451) | 9.963 (0.791) | 7.353 (0.380) |
| Â | 24 | 17.770 (1.462) | 14.257 (0.297) | 9.740 (0.986) |
| Â | 72 | 18.700 (0.360) | 16.593 (0.756) | 9.627 (0.997) |