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  1. Three-dimensional photopolymerization techniques such as multiphoton polymerization lithography (MPL) and stimulated emission depletion (STED) lithography are powerful tools for fabricating structures in the s...

    Authors: Bianca Buchegger, Alexander Tanzer, Sandra Posch, Christian Gabriel, Thomas A. Klar and Jaroslaw Jacak

    Citation: Journal of Nanobiotechnology 2021 19:23

    Content type: Short Communication

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  2. Breast cancer (BC) is the most frequently diagnosed cancer and the leading cause of cancer-associated deaths in women. Recent studies have indicated that microRNA (miRNA) regulation in genomic instability (GI)...

    Authors: Siqi Bao, Ting Hu, Jiaqi Liu, Jianzhong Su, Jie Sun, Yue Ming, Jiaxin Li, Nan Wu, Hongyan Chen and Meng Zhou

    Citation: Journal of Nanobiotechnology 2021 19:22

    Content type: Research

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  3. Nanoparticles are being increasingly used in biomedical applications owing to their unique physical and chemical properties and small size. However, their biophysical assessment and evaluation of side-effects ...

    Authors: Tae Hwan Shin, Abdurazak Aman Ketebo, Da Yeon Lee, Seungah Lee, Seong Ho Kang, Shaherin Basith, Balachandran Manavalan, Do Hyeon Kwon, Sungsu Park and Gwang Lee

    Citation: Journal of Nanobiotechnology 2021 19:21

    Content type: Research

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  4. Accumulating evidence shows that mesenchymal stem cell-derived extracellular vesicles (EVs) hold great promise to promote hair growth. However, large-scale production of EVs is still a challenge. Recently, exo...

    Authors: Lei Cao, Tian Tian, Yuanbo Huang, Shiqin Tao, Xiaohong Zhu, Mifang Yang, Jing Gu, Guangdong Feng, Yinni Ma, Rushan Xia, Wenrong Xu and Lei Wang

    Citation: Journal of Nanobiotechnology 2021 19:20

    Content type: Research

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  5. Incidence of pulmonary aspergillosis is rising worldwide, owing to an increased population of immunocompromised patients. Notable potential of the pulmonary route has been witnessed in antifungal delivery due ...

    Authors: Ranjot Kaur, Sarah R. Dennison, Andrea J. Burrow, Shivaprakash M. Rudramurthy, Rajan Swami, Varun Gorki, O. P. Katare, Anupama Kaushik, Bhupinder Singh and Kamalinder K. Singh

    Citation: Journal of Nanobiotechnology 2021 19:19

    Content type: Research

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  6. The combination therapy which has been proposed as the strategy for the cancer treatment could achieve a synergistic effect for cancer therapies and reduce the dosage of the applied drugs. On account of the th...

    Authors: Fatemeh Abedi, Soodabeh Davaran, Malak Hekmati, Abolfazl Akbarzadeh, Behzad Baradaran and Sevil Vaghefi Moghaddam

    Citation: Journal of Nanobiotechnology 2021 19:18

    Content type: Research

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  7. Chemotherapy and gene therapy are used in clinical practice for the treatment of castration-resistant prostate cancer. However, the poor efficiency of drug delivery and serious systemic side effects remain an ...

    Authors: Yiran Zhang, Yanming Wang, Li Meng, Qingqing Huang, Yueqi Zhu, Wenguo Cui, Yingsheng Cheng and Ranlu Liu

    Citation: Journal of Nanobiotechnology 2021 19:17

    Content type: Research

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  8. Tumor-targeted nanoparticles hold great promise as new tools for therapy of liquid cancers. Furthermore, the therapeutic efficacy of nanoparticles can be improved by enhancing the cancer cellular internalization.

    Authors: Kai-Wen Ho, I.-J.u Chen, Yi-An Cheng, Tzu-Yi Liao, En-Shuo Liu, Huei-Jen Chen, Yun-Chi Lu, Yu-Cheng Su, Steve R. Roffler, Bo-Cheng Huang, Hui-Ju Liu, Ming-Yii Huang, Chiao-Yun Chen and Tian-Lu Cheng

    Citation: Journal of Nanobiotechnology 2021 19:16

    Content type: Research

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  9. There is a strong need for non-invasive and patient-friendly delivery systems of protein drugs for long-term therapy. However, oral delivery of protein drugs is a big challenge due to many barriers including i...

    Authors: Jae Geun Song, Sang Hoon Lee and Hyo-Kyung Han

    Citation: Journal of Nanobiotechnology 2021 19:15

    Content type: Research

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  10. Nano-drug delivery systems show considerable promise for effective cancer therapy. Polymeric micelles have attracted extensive attention as practical nanocarriers for target drug delivery and controlled drug d...

    Authors: Changzhen Sun, Ji Lu, Jun Wang, Ping Hao, Chunhong Li, Lu Qi, Lin Yang, Bin He, Zhirong Zhong and Na Hao

    Citation: Journal of Nanobiotechnology 2021 19:14

    Content type: Research

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  11. To date, triple-negative breast cancer (TNBC) treatment options are limited because of the loss of target receptors and, as a result, are only managed with chemotherapy. What is worse is that TNBC is frequentl...

    Authors: Long Zhang, Chaofeng Mu, Tinghong Zhang, Dejun Yang, Chenou Wang, Qiong Chen, Lin Tang, Luhui Fan, Cong Liu, Jianliang Shen and Huaqiong Li

    Citation: Journal of Nanobiotechnology 2021 19:13

    Content type: Research

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  12. After the golden age of antibiotic discovery, bacterial infections still represent a major challenge for public health worldwide. The biofilm mode of growth is mostly responsible for chronic infections that cu...

    Authors: David Da Costa, Chloé Exbrayat-Héritier, Basile Rambaud, Simon Megy, Raphaël Terreux, Bernard Verrier and Charlotte Primard

    Citation: Journal of Nanobiotechnology 2021 19:12

    Content type: Research

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  13. Breast cancer bone metastasis has become one of the most common complications; however, it may cause cancer recurrence and bone nonunion, as well as local bone defects.

    Authors: Yu-Wei Ge, Xiao-Liang Liu, De-gang Yu, Zhen-An Zhu, Qin-Fei Ke, Yuan-Qing Mao, Ya-Ping Guo and Jing-Wei Zhang

    Citation: Journal of Nanobiotechnology 2021 19:11

    Content type: Research

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  14. Advantages of polymeric nanoparticles as drug delivery systems include controlled release, enhanced drug stability and bioavailability, and specific tissue targeting. Nanoparticle properties such as hydrophobi...

    Authors: Sean Swetledge, Jangwook P. Jung, Renee Carter and Cristina Sabliov

    Citation: Journal of Nanobiotechnology 2021 19:10

    Content type: Review

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  15. Phototherapy is a promising strategy for cancer therapy by reactive oxygen species (ROS) of photodynamic therapy (PDT) and hyperthermia of photothermal therapy (PTT). However, the therapeutic efficacy was rest...

    Authors: Gutian Zhang, Wenting Cheng, Lin Du, Chuanjun Xu and Jinlong Li

    Citation: Journal of Nanobiotechnology 2021 19:9

    Content type: Research

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  16. Non-Hodgkin’s lymphoma (NHL) possesses great heterogeneity in cytogenetics, immunophenotype and clinical features, and chemotherapy currently serves as the main treatment modality. Although employing monoclona...

    Authors: Qiangqiang Zhao, Xiaoying Sun, Bin Wu, Yinghui Shang, Xueyuan Huang, Hang Dong, Haiting Liu, Wansong Chen, Rong Gui and Jian Li

    Citation: Journal of Nanobiotechnology 2021 19:8

    Content type: Research

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  17. Tumor cell-derived exosomes (TEx) have emerged as promising nanocarriers for drug delivery. Noninvasive multimodality imaging for tracing the in vivo trafficking of TEx may accelerate their clinical translatio...

    Authors: Boping Jing, Yongkang Gai, Ruijie Qian, Zhen Liu, Ziyang Zhu, Yu Gao, Xiaoli Lan and Rui An

    Citation: Journal of Nanobiotechnology 2021 19:7

    Content type: Research

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  18. Mitochondrial dysfunction is a critical factor in the onset and progression of neurodegenerative diseases. Recently, mitochondrial transplantation has been advised as an innovative and attractive strategy to t...

    Authors: Pasquale Picone, Gaetana Porcelli, Celeste Caruso Bavisotto, Domenico Nuzzo, Giacoma Galizzi, Pier Luigi San Biagio, Donatella Bulone and Marta Di Carlo

    Citation: Journal of Nanobiotechnology 2021 19:6

    Content type: Research

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  19. A positive surface charge has been largely associated with nanoparticle (NP) toxicity. However, by screening a carbon NP library in macrophages, we found that a cationic charge does not systematically translat...

    Authors: Maud Weiss, Jiahui Fan, Mickaël Claudel, Thomas Sonntag, Pascal Didier, Carole Ronzani, Luc Lebeau and Françoise Pons

    Citation: Journal of Nanobiotechnology 2021 19:5

    Content type: Research

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  20. The integration of multiple functions with organic polymers-based nanoagent holds great potential to potentiate its therapeutic efficacy, but still remains challenges. In the present study, we design and prepa...

    Authors: Fangpeng Shu, Taowei Yang, Xuefeng Zhang, Wenbin Chen, Kaihui Wu, Junqi Luo, Xumin Zhou, Guochang Liu, Jianming Lu and Xiangming Mao

    Citation: Journal of Nanobiotechnology 2021 19:4

    Content type: Research

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  21. Despite the highly expected clinical application of nanoparticles (NPs), the translation of NPs from lab to the clinic has been relatively slow. Co-culture 3D spheroids account for the 3D arrangement of tumor ...

    Authors: Ilya Yakavets, Aurelie Francois, Laureline Lamy, Max Piffoux, Florence Gazeau, Claire Wilhelm, Vladimir Zorin, Amanda K. A. Silva and Lina Bezdetnaya

    Citation: Journal of Nanobiotechnology 2021 19:3

    Content type: Research

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  22. The rise of nanotechnology and widespread use of engineered nanomaterials in everyday human life has led to concerns regarding their potential effect on human health. Adverse effects of nanomaterials and nanop...

    Authors: Marta Pogribna and George Hammons

    Citation: Journal of Nanobiotechnology 2021 19:2

    Content type: Review

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  23. Skin is the body’s first barrier against external pathogens that maintains the homeostasis of the body. Any serious damage to the skin could have an impact on human health and quality of life. Tissue engineeri...

    Authors: Hamed Nosrati, Reza Aramideh Khouy, Ali Nosrati, Mohammad Khodaei, Mehdi Banitalebi-Dehkordi, Korosh Ashrafi-Dehkordi, Samira Sanami and Zohreh Alizadeh

    Citation: Journal of Nanobiotechnology 2021 19:1

    Content type: Review

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  25. Breast cancer continues to be the most frequently diagnosed malignancy among women, putting their life in jeopardy. Cancer immunotherapy is a novel approach with the ability to boost the host immune system to ...

    Authors: Amirhossein Bahreyni, Yasir Mohamud and Honglin Luo

    Citation: Journal of Nanobiotechnology 2020 18:180

    Content type: Review

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  26. Inflammation and oxidative stress are two major factors that are involved in the pathogenesis of atherosclerosis. A smart drug delivery system that responds to the oxidative microenvironment of atherosclerotic...

    Authors: Dan Mu, Jianhui Li, Yu Qi, Xuan Sun, Yihai Liu, Song Shen, Yuyu Li, Biao Xu and Bing Zhang

    Citation: Journal of Nanobiotechnology 2020 18:179

    Content type: Research

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  27. Mesenchymal stem cells (MSCs) are pluripotent stromal cells that release extracellular vesicles (EVs). EVs contain various growth factors and antioxidants that can positively affect the surrounding cells. Nano...

    Authors: Dong Jun Park, Wan Su Yun, Woo Cheol Kim, Jeong-Eun Park, Su Hoon Lee, Sunmok Ha, Jin Sil Choi, Jaehong Key and Young Joon Seo

    Citation: Journal of Nanobiotechnology 2020 18:178

    Content type: Research

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  28. Chemotherapy is often a first-line therapeutic approach for the treatment of a wide variety of cancers. Targeted drug delivery systems (DDSs) can potentially resolve the problem of chemotherapeutic drug off-ta...

    Authors: Anna Florczak, Tomasz Deptuch, Anna Lewandowska, Karolina Penderecka, Elzbieta Kramer, Andrzej Marszalek, Andrzej Mackiewicz and Hanna Dams-Kozlowska

    Citation: Journal of Nanobiotechnology 2020 18:177

    Content type: Research

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  29. Diabetes mellitus is one of the most common metabolic disorders. One of the important metabolic complications in diabetes is diabetic foot ulcer syndrome, which causes delayed and abnormal healing of the wound...

    Authors: Payam Khazaeli, Maryam Alaei, Mohammad Khaksarihadad and Mehdi Ranjbar

    Citation: Journal of Nanobiotechnology 2020 18:176

    Content type: Research

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  30. Development of sensitive and specific imaging approaches for the detection of ovarian cancer holds great promise for improving the therapeutic efficacy and the lifespan of the patients.

    Authors: Cuiping Han, Ting Xie, Keying Wang, Shang Jin, Ke Li, Peipei Dou, Nana Yu and Kai Xu

    Citation: Journal of Nanobiotechnology 2020 18:175

    Content type: Research

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  31. Treatment of patients affected by severe burns is challenging, especially due to the high risk of Pseudomonas infection. In the present work, we have generated a novel model of bioartificial human dermis substitu...

    Authors: Jesús Chato-Astrain, Isabel Chato-Astrain, David Sánchez-Porras, Óscar-Darío García-García, Fabiola Bermejo-Casares, Claudia Vairo, María Villar-Vidal, Garazi Gainza, Silvia Villullas, Roke-Iñaki Oruezabal, Ángela Ponce-Polo, Ingrid Garzón, Víctor Carriel, Fernando Campos and Miguel Alaminos

    Citation: Journal of Nanobiotechnology 2020 18:174

    Content type: Research

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  32. MiRNAs act as negative regulators of gene expression through target mRNA degradation or inhibition of its translation. In cancer, several miRNAs are upregulated and play crucial roles in tumorigenesis, making ...

    Authors: Manfred Kunz, Madeleine Brandl, Animesh Bhattacharya, Lars Nobereit-Siegel, Alexander Ewe, Ulrike Weirauch, Doreen Hering, Anja Reinert, Hermann Kalwa, Juan Guzman, Katrin Weigelt, Sven Wach, Helge Taubert and Achim Aigner

    Citation: Journal of Nanobiotechnology 2020 18:173

    Content type: Research

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  33. Capping agents are of utmost importance as stabilizers that inhibit the over-growth of nanoparticles and prevent their aggregation/coagulation in colloidal synthesis. The capping ligands stabilize the interfac...

    Authors: Rabia Javed, Muhammad Zia, Sania Naz, Samson O. Aisida, Noor ul Ain and Qiang Ao

    Citation: Journal of Nanobiotechnology 2020 18:172

    Content type: Review

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  34. Human trophoblast stem cells (TSCs) have been confirmed to play a cardioprotective role in heart failure. However, whether trophoblast stem cell-derived exosomes (TSC-Exos) can protect cardiomyocytes from doxo...

    Authors: Jie Ni, Yihai Liu, Lina Kang, Lian Wang, Zhonglin Han, Kun Wang, Biao Xu and Rong Gu

    Citation: Journal of Nanobiotechnology 2020 18:171

    Content type: Research

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  35. Nanoparticles (NPs) can enter cells and cause cellular dysfunction. For example, reactive oxygen species generated by NPs can damage the cytoskeleton and impair cellular adhesion properties. Previously, we rep...

    Authors: Abdurazak Aman Ketebo, Tae Hwan Shin, Myeongjun Jun, Gwang Lee and Sungsu Park

    Citation: Journal of Nanobiotechnology 2020 18:170

    Content type: Research

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  36. It is very important to develop a highly efficient cerebrospinal fluid (CSF) detection system with diagnosis and prediction function, for which the detection of circulating tumor cells (CTCs) in CSF is a good ...

    Authors: Yang Zhao, Feng Jiang, Qinhua Wang, Baocheng Wang, Yipeng Han, Jian Yang, Jiajia Wang, Kai Wang, Junping Ao, Xunxiang Guo, Xiaofei Liang and Jie Ma

    Citation: Journal of Nanobiotechnology 2020 18:169

    Content type: Research

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  37. Monocyte/macrophage-targeting delivery systems (MTDSs) have been focused upon as an emerging routine for delivering drugs to treat various macrophage-related diseases. However, the ability of MTDSs to distingu...

    Authors: Yuchuan Yuan, Ling Long, Jiaxing Liu, Yongyao Lin, Cuiping Peng, Yue Tang, Xuemei Zhou, Shuhui Li, Chengyuan Zhang, Xiaohui Li and Xing Zhou

    Citation: Journal of Nanobiotechnology 2020 18:168

    Content type: Research

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  38. Low-density lipoprotein (LDL) is an important plasma lipoprotein transporting lipids to peripheral tissues/cells. The oxidation of LDL plays critical roles in atherogenesis and its oxidized form (oxLDL) is an ...

    Authors: Kun Wang, Yuanfang Li, Chao Luo and Yong Chen

    Citation: Journal of Nanobiotechnology 2020 18:167

    Content type: Short Communication

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  39. Studying bacterial adhesion and early biofilm development is crucial for understanding the physiology of sessile bacteria and forms the basis for the development of novel antimicrobial biomaterials. Microfluid...

    Authors: Hervé Straub, Leo Eberl, Manfred Zinn, René M. Rossi, Katharina Maniura-Weber and Qun Ren

    Citation: Journal of Nanobiotechnology 2020 18:166

    Content type: Research

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  40. Trunk-boring pests (TBPs) are an important type of forest pest, TBPs not only feed on the branches and trunks of trees, but also spread quarantine diseases in forests. However, because the larvae of TBPs live ...

    Authors: Chenyu Su, Shanshan Liu, Shenghan Cao, Shuyan Yin, Chenggang Zhou, Shangkun Gao, Chunyan Jia, Yingchao Ji and Yanxue Liu

    Citation: Journal of Nanobiotechnology 2020 18:165

    Content type: Research

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  41. Combination chemotherapy uses drugs that target different cancer hallmarks, resulting in synergistic or additive toxicity. This strategy enhances therapeutic efficacy as well as minimizes drug resistance and s...

    Authors: Renata Rank Miranda, Micaella Pereira da Fonseca, Barbara Korzeniowska, Lilian Skytte, Kaare Lund Rasmussen and Frank Kjeldsen

    Citation: Journal of Nanobiotechnology 2020 18:164

    Content type: Research

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  42. Umbilical cord mesenchymal stem cell (HUCMSC)-based therapies were previously utilised for cartilage regeneration because of the chondrogenic potential of MSCs. However, chondrogenic differentiation of HUCMSCs...

    Authors: Ke Ma, Bo Zhu, Zetao Wang, Peian Cai, Mingwei He, Danyan Ye, Guohua Yan, Li Zheng, Lujun Yang and Jinmin Zhao

    Citation: Journal of Nanobiotechnology 2020 18:163

    Content type: Research

    Published on:

  43. Cancer cell-derived extracellular vesicles (EVs) have previously been shown to contribute to pre-metastatic niche formation. Specifically, aggressive tumors secrete pro-metastatic EVs that travel in the circul...

    Authors: Sara Busatto, Yubo Yang, Sierra A. Walker, Irina Davidovich, Wan-Hsin Lin, Laura Lewis-Tuffin, Panagiotis Z. Anastasiadis, Jann Sarkaria, Yeshayahu Talmon, Gregory Wurtz and Joy Wolfram

    Citation: Journal of Nanobiotechnology 2020 18:162

    Content type: Research

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  44. Most cancers favor glycolytic-based glucose metabolism. Hexokinase-2 (HK2), the first glycolytic rate-limiting enzyme, shows limited expression in normal adult tissues but is overexpressed in many tumor tissue...

    Authors: Meng Zhang, Qiyu Liu, Mingxing Zhang, Cong Cao, Xiaoxia Liu, Mengyu Zhang, Guiling Li, Congjian Xu and Xiaoyan Zhang

    Citation: Journal of Nanobiotechnology 2020 18:161

    Content type: Research

    Published on:

  45. Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. No disease-modifying strategy to prevent or delay AD progression currently exists. Aβ oligomers (AβOs), rather than monomers or fibrils, ar...

    Authors: Xiao-ge Liu, Lun Zhang, Shuai Lu, Dong-qun Liu, Ya-ru Huang, Jie Zhu, Wei-wei Zhou, Xiao-lin Yu and Rui-tian Liu

    Citation: Journal of Nanobiotechnology 2020 18:160

    Content type: Research

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  46. Purification of recombinant proteins is often a challenging matter because high purity and high recovery are desired. If the expressed recombinant protein is also in a complex matrix, such as from the silkworm...

    Authors: Robert Minkner, Jian Xu, Kenshin Takemura, Jirayu Boonyakida, Hermann Wätzig and Enoch Y. Park

    Citation: Journal of Nanobiotechnology 2020 18:159

    Content type: Research

    Published on:

  47. MiRNA-150, a gene regulator that has been revealed to be abnormal expression in non-small cell lung cancer (NSCLC), can be regarded as a serum indicator for diagnosis and monitoring of NSCLC. Herein, a new sor...

    Authors: Huiyan Tian, Changjing Yuan, Yu Liu, Zhi Li, Ke Xia, Mengya Li, Fengxin Xie, Qinghai Chen, Ming Chen, Weiling Fu and Yang Zhang

    Citation: Journal of Nanobiotechnology 2020 18:158

    Content type: Research

    Published on:

  48. The chemotherapy drug doxorubicin (Dox) is widely used for treating a variety of cancers. However, its high cardiotoxicity hampered its clinical use. Exosomes derived from stem cells showed a therapeutic effec...

    Authors: Lei Zhuang, Wenzheng Xia, Didi Chen, Yijia Ye, Tingting Hu, Shiting Li and Meng Hou

    Citation: Journal of Nanobiotechnology 2020 18:157

    Content type: Research

    Published on:

  49. Infectious diseases kill over 17 million people a year, among which bacterial infections stand out. From all the bacterial infections, tuberculosis, diarrhoea, meningitis, pneumonia, sexual transmission diseas...

    Authors: Amanda Cano, Miren Ettcheto, Marta Espina, Ana López-Machado, Yolanda Cajal, Francesc Rabanal, Elena Sánchez-López, Antonio Camins, Maria Luisa García and Eliana B. Souto

    Citation: Journal of Nanobiotechnology 2020 18:156

    Content type: Review

    Published on:

  50. Multifunctional lanthanide-based upconversion nanoparticles (UCNPs), which feature efficiently convert low-energy photons into high-energy photons, have attracted considerable attention in the domain of materi...

    Authors: Gaofeng Liang, Haojie Wang, Hao Shi, Haitao Wang, Mengxi Zhu, Aihua Jing, Jinghua Li and Guangda Li

    Citation: Journal of Nanobiotechnology 2020 18:154

    Content type: Review

    Published on:

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