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  1. A method with high sensitivity, good accuracy and fast response is of ever increasing importance for the simultaneous detection of AA, DA and UA. In this paper, a simple and sensitive electrochemical sensor, w...

    Authors: Yiyong Wu, Peihong Deng, Yaling Tian, Jinxia Feng, Jingyun Xiao, Junhua Li, Jun Liu, Guangli Li and Quanguo He

    Citation: Journal of Nanobiotechnology 2020 18:112

    Content type: Research

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  2. Electrospun (e-spun) nanofibers for wound dressing have attracted wide attention due to its large specific surface area, large porosity and breathability. Compared with solution electrospinning (e-spinning), m...

    Authors: Ying-Tao Zhao, Jun Zhang, Yuan Gao, Xiao-Fei Liu, Jiang-Jun Liu, Xiao-Xiong Wang, Hong-Fei Xiang and Yun-Ze Long

    Citation: Journal of Nanobiotechnology 2020 18:111

    Content type: Research

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  3. Due to the unexpected side effects of the iodinated contrast agents, novel contrast agents for X-ray computed tomography (CT) imaging are urgently needed. Nanoparticles made by heavy metal elements are often e...

    Authors: Ji-jun Fu, Jun-jie Guo, Ai-ping Qin, Xi-yong Yu, Qiang Zhang, Xue-ping Lei, Yu-gang Huang, Ming-yue Chen, Jie-xia Li, Yu Zhang, Jing-ping Liu, Yuan-ye Dang, Dan Wu, Xiao-ya Zhao, Zhong-xiao Lin, Yin-lei Lin…

    Citation: Journal of Nanobiotechnology 2020 18:110

    Content type: Research

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  4. Antisense oligonucleotides (ASOs) based technology is considered a potential strategy against antibiotic-resistant bacteria; however, a major obstacle to the application of ASOs is how to deliver them into bac...

    Authors: Yue Hu, Zhou Chen, Xinggang Mao, Mingkai Li, Zheng Hou, Jingru Meng, Xiaoxing Luo and Xiaoyan Xue

    Citation: Journal of Nanobiotechnology 2020 18:109

    Content type: Research

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  5. Drug delivery systems (DDSs) based on nanomaterials have shown a promise for cancer chemotherapy; however, it remains a great challenge to localize on-demand release of anticancer drugs in tumor tissues to imp...

    Authors: Xiaoying Wang, Zeliang Xuan, Xiaofeng Zhu, Haitao Sun, Jingchao Li and Zongyu Xie

    Citation: Journal of Nanobiotechnology 2020 18:108

    Content type: Review

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  6. Tuberculosis (TB) is a highly infectious disease caused by Mycobacterium tuberculosis (Mtb), which often parasites in macrophages. This study is performed to investigate the bactericidal effect and underlying mec...

    Authors: Shuang Xie, Gangjing Li, Yuru Hou, Min Yang, Fahui Li, Jianhu Li, Dairong Li and Yonghong Du

    Citation: Journal of Nanobiotechnology 2020 18:107

    Content type: Research

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  7. Topical isotretinoin is commonly used to treat acne. However, topical isotretinoin has side effects and can hardly permeate through the stratum corneum, the most important skin barrier. Therefore, this study a...

    Authors: Shiyi Wang, Rihua Jiang, Tianqi Meng, Fuqiang Zhang, Jing Li, Yongri Jin, JeungHoon Lee, Mingji Zhu and Jinlan Jiang

    Citation: Journal of Nanobiotechnology 2020 18:106

    Content type: Research

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  8. Spinal cord injury (SCI) is a catastrophic injury that can cause irreversible motor dysfunction with high disability. Exosomes participate in the transport of miRNAs and play an essential role in intercellular...

    Authors: Dongdong Jiang, Fangyi Gong, Xuhui Ge, Chengtang Lv, Chenyu Huang, Shuang Feng, Zheng Zhou, Yuluo Rong, Jiaxing Wang, Chengyue Ji, Jian Chen, Wene Zhao, Jin Fan, Wei Liu and Weihua Cai

    Citation: Journal of Nanobiotechnology 2020 18:105

    Content type: Research

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  9. This study aimed to develop a ternary nanocomposite system of organoclay, glycol-chitosan, and Eudragit®S100 as an effective colon targeted drug delivery carrier to enhance the oral absorption of insulin. A nanoc...

    Authors: Sang Hoon Lee, Seung-Yun Back, Jae Geun Song and Hyo-Kyung Han

    Citation: Journal of Nanobiotechnology 2020 18:104

    Content type: Research

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  10. Selenium (Se) in soil mainly consists of selenite, selenate, and elemental Se. However, little is known about the mechanism involved in the uptake and biotransformation of elemental Se by plants.

    Authors: Kang Wang, Yaqi Wang, Kui Li, Yanan Wan, Qi Wang, Zhong Zhuang, Yanbin Guo and Huafen Li

    Citation: Journal of Nanobiotechnology 2020 18:103

    Content type: Research

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  11. In this study, a multifunctional tetraphenylporphyrin (TPP) conjugated polyethylene glycol with biotin (TPP-PEG-biotin) as a photo-dynamic therapy (PDT) material encapsulating a ruthenium complex 1 (Ru-1) was ...

    Authors: Baskaran Purushothaman, Jeongmin Lee, Sera Hong and Joon Myong Song

    Citation: Journal of Nanobiotechnology 2020 18:102

    Content type: Research

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  12. Cell membrane-based nanocarriers are promising candidates for delivering antitumor agents. The employment of a simple and feasible method to improve the tumor-targeting abilities of these systems is appealing ...

    Authors: Yin Chen, Xue Shen, Songling Han, Tao Wang, Jianqi Zhao, Yongwu He, Shilei Chen, Shengqi Deng, Cheng Wang and Junping Wang

    Citation: Journal of Nanobiotechnology 2020 18:101

    Content type: Research

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  13. Plant-derived extracellular vesicles (PDEVs) have great potential for clinical applications. Ultracentrifugation, considered the gold standard method for the preparation of PDEVs, is efficacious but time-consu...

    Authors: Meng Yang, Xiaoyan Liu, Qingqiong Luo, Lili Xu and Fuxiang Chen

    Citation: Journal of Nanobiotechnology 2020 18:100

    Content type: Research

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  14. CuS-modified hollow mesoporous organosilica nanoparticles (HMON@CuS) have been preferred as non-invasive treatment for cancer, as near infrared (NIR)-induced photo-thermal effect (PTT) and/or photo-dynamic eff...

    Authors: Weihong Guo, Zhian Chen, Jiajia Chen, Xiaoli Feng, Yang Yang, Huilin Huang, Yanrui Liang, Guodong Shen, Yu Liang, Chao Peng, Yanbing Li, Guoxin Li, Wenhua Huang, Bingxia Zhao and Yanfeng Hu

    Citation: Journal of Nanobiotechnology 2020 18:99

    Content type: Research

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  15. In this study, we aimed to design a novel oral insulin delivery system, named “oil-soluble” reversed lipid nanoparticles (ORLN), in which a hydrophilic insulin molecule is encapsulated by a phospholipid (PC) s...

    Authors: Tao Wang, Liao Shen, Yadan Zhang, Haiyan Li, Yongan Wang and Dongqin Quan

    Citation: Journal of Nanobiotechnology 2020 18:98

    Content type: Research

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  16. Three-dimensional (3D) printing involves the layering of seed cells, biologically compatible scaffolds, and biological activity factors to precisely recapitulate a biological tissue. Graphene oxide (GO), a typ...

    Authors: Zhong Cheng, Li Xigong, Diao Weiyi, Hu Jingen, Wang Shuo, Lin Xiangjin and Wu Junsong

    Citation: Journal of Nanobiotechnology 2020 18:97

    Content type: Research

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  17. The traditional treatment for diabetes usually requires frequent insulin injections to maintain normoglycemia, which is painful and difficult to achieve blood glucose control.

    Authors: Xia Zhou, Hongwei Wu, Ruimin Long, Shibin Wang, Haiwang Huang, Yanhua Xia, Pei Wang, Yifeng Lei, Yuanyuan Cai, Duanhua Cai and Yuangang Liu

    Citation: Journal of Nanobiotechnology 2020 18:96

    Content type: Research

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  18. Currently, the diagnosis and treatment of neuroblastomas—the most frequent solid tumors in children—exploit the norepinephrine transporter (hNET) via radiolabeled norepinephrine analogs. We aim to develop a na...

    Authors: Yazan Haddad, Marketa Charousova, Hana Zivotska, Zbynek Splichal, Miguel Angel Merlos Rodrigo, Hana Michalkova, Sona Krizkova, Barbora Tesarova, Lukas Richtera, Petr Vitek, Kamila Stokowa-Soltys, David Hynek, Vedran Milosavljevic, Simona Rex and Zbynek Heger

    Citation: Journal of Nanobiotechnology 2020 18:95

    Content type: Research

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  19. Celastrol has been proven effective in anti-inflammatory but was limited in the clinic due to the poor solubility and side effects induced by low bioavailability. Osteoarthritis has acidic and inflammatory env...

    Authors: Tian Jin, Di Wu, Xiao-Ming Liu, Jiang-Tao Xu, Bing-Jie Ma, Yun Ji, Yu-Ying Jin, Si-Yin Wu, Tao Wu and Ke Ma

    Citation: Journal of Nanobiotechnology 2020 18:94

    Content type: Research

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  20. Since vascular endothelial growth factor (VEGF) is a significant regulator of cancer angiogenesis, it is essential to develop a technology for its sensitive detection. Herein, we sensitized a chemiluminescence...

    Authors: Fahimeh Ghavamipour, Hossein Rahmani, Maryam Shanehsaz, Khosro Khajeh, Manouchehr Mirshahi and Reza H. Sajedi

    Citation: Journal of Nanobiotechnology 2020 18:93

    Content type: Research

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  21. Cell membrane- covered drug-delivery nanoplatforms have been garnering attention because of their enhanced bio-interfacing capabilities that originate from source cells. In this top-down technique, nanoparticl...

    Authors: Chunai Gong, Xiaoyan Yu, Benming You, Yan Wu, Rong Wang, Lu Han, Yujie Wang, Shen Gao and Yongfang Yuan

    Citation: Journal of Nanobiotechnology 2020 18:92

    Content type: Research

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  22. Ovarian cancer is a highly aggressive malignant disease in gynecologic cancer. It is an urgent task to develop three-dimensional (3D) cell models in vitro and dissect the cell progression-related drug resistan...

    Authors: Hong Song, Guo-hui Cai, Jian Liang, Di-shu Ao, Huan Wang and Ze-hong Yang

    Citation: Journal of Nanobiotechnology 2020 18:90

    Content type: Research

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  23. Farnesol is a sesquiterpene from propolis and citrus fruit that shows promising anti-bacterial activity for caries treatment and prevention, but its hydrophobicity limits the clinical application. We aimed to ...

    Authors: Youping Yi, Lujun Wang, Lin Chen, Yan Lin, Zhongling Luo, Zhenyu Chen, Ting Li, Jianming Wu and Zhirong Zhong

    Citation: Journal of Nanobiotechnology 2020 18:89

    Content type: Research

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  24. Nanocomposite hydrogels capable of undergoing manufacturing process have recently attracted attention in biomedical applications due to their desired mechanical properties and high functionality. 3D printing n...

    Authors: Dae Gon Lim, Eunah Kang and Seong Hoon Jeong

    Citation: Journal of Nanobiotechnology 2020 18:88

    Content type: Research

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  25. Hepatic stellate cells (HSCs) were activated and secreted excessive amounts of extracellular matrix (ECM) proteins during pathogenetic progress of liver fibrosis. Germacrone (GMO) and miR-29b can play an impor...

    Authors: De Ji, Qiaohan Wang, Qi Zhao, Huangjin Tong, Mengting Yu, Meng Wang, Tulin Lu and Chengxi Jiang

    Citation: Journal of Nanobiotechnology 2020 18:86

    Content type: Research

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  26. The unique upconversion properties of rare-earth-doped nanoparticles offers exciting opportunities for biomedical applications, in which near-IR remote activation of biological processes is desired, including ...

    Authors: Raquel Martínez, Ester Polo, Silvia Barbosa, Pablo Taboada, Pablo del Pino and Beatriz Pelaz

    Citation: Journal of Nanobiotechnology 2020 18:85

    Content type: Research

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  27. Fracture incidence increases with ageing and other contingencies. However, the strategy of accelerating fracture repair in clinical therapeutics remain a huge challenge due to its complexity and a long-lasting...

    Authors: Shunhao Wang, Jiahuang Qiu, Anyi Guo, Ruanzhong Ren, Wei He, Sijin Liu and Yajun Liu

    Citation: Journal of Nanobiotechnology 2020 18:84

    Content type: Research

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  28. Breast cancer lung metastasis occurs in more than 60% of all patients with breast cancer, and most of those afflicted by it eventually die of recurrence. The tumor microenvironment plays vital roles in metasta...

    Authors: Ying Liu, Xingmei Xie, Xuefeng Hou, Junyi Shen, Jiangpei Shi, Haizhen Chen, Yuanzhi He, Zhi Wang and Nianping Feng

    Citation: Journal of Nanobiotechnology 2020 18:83

    Content type: Research

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  29. Dysfunction of human respiratory and electro-cardiac activities could affect the ability of the heart to pump blood and the lungs to inhale oxygen. Thus, a device could simultaneously measure electro-cardiac s...

    Authors: Li Wang, Feng Zhang, Kechao Lu, Mohammed Abdulaziz, Chao Li, Chongyu Zhang, Jun Chen and Yunlun Li

    Citation: Journal of Nanobiotechnology 2020 18:82

    Content type: Research

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  30. Bacterial biofilms are communities of surface-associated microorganisms living in cellular clusters or micro-colonies, encapsulated in a complex matrix composed of an extracellular polymeric substance, separat...

    Authors: Ella Yeor-Davidi, Marina Zverzhinetsky, Vadim Krivitsky and Fernando Patolsky

    Citation: Journal of Nanobiotechnology 2020 18:81

    Content type: Research

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  31. Psoriasis is a chronic immune-mediated inflammatory skin disease without effective treatment. The utilization of all trans-retinoic acid (TRA) and betamethasone (BT) for the treatment of psoriasis is still fac...

    Authors: Wei Wang, Gao-feng Shu, Kong-jun Lu, Xiao-ling Xu, Min-cheng Sun, Jing Qi, Qiao-ling Huang, Wei-qiang Tan and Yong-zhong Du

    Citation: Journal of Nanobiotechnology 2020 18:80

    Content type: Research

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  32. An amendment to this paper has been published and can be accessed via the original article.

    Authors: K. Marycz, P. Sobierajska, M. Roecken, K. Kornicka-Garbowska, M. Kępska, R. Idczak, J.-M. Nedelec and R. J. Wiglusz

    Citation: Journal of Nanobiotechnology 2020 18:79

    Content type: Correction

    Published on:

    The original article was published in Journal of Nanobiotechnology 2020 18:33

  33. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Jiayi Gu, Yuming Chen, Ling Tong, Xueling Wang, Dehong Yu and Hao Wu

    Citation: Journal of Nanobiotechnology 2020 18:78

    Content type: Correction

    Published on:

    The original article was published in Journal of Nanobiotechnology 2020 18:53

  34. Most nanoparticles (NPs) reportedly block autophagic flux, thereby upregulating p62/SQSTM1 through degradation inhibition. p62 also acts as a multifunctional scaffold protein with multiple domains, and is invo...

    Authors: Yifan Wu, Yang Jin, Tianyu Sun, Piaoyu Zhu, Jinlong Li, Qinglin Zhang, Xiaoke Wang, Junkang Jiang, Gang Chen and Xinyuan Zhao

    Citation: Journal of Nanobiotechnology 2020 18:77

    Content type: Research

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  35. Formation of muscular pseudo-tissue depends on muscle precursor cells, the extracellular matrix (ECM)-mimicking structure and factors stimulating cell differentiation. These three things cooperate and can crea...

    Authors: Marlena Zielińska-Górska, Anna Hotowy, Mateusz Wierzbicki, Jaśmina Bałaban, Malwina Sosnowska, Sławomir Jaworski, Barbara Strojny, André Chwalibog and Ewa Sawosz

    Citation: Journal of Nanobiotechnology 2020 18:76

    Content type: Research

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  36. Nordihydroguaiaretic acid (NDGA) is a plant lignan obtained from creosote bush, known to possess anti-oxidant, anti-cancer and anti-viral activities and is being used in traditional medicine. However, toxicity...

    Authors: Geraldine Sandana Mala John, Veena Kumari Vuttaradhi, Satoru Takeuchi, Ravi Shankar Pitani, Ganesh Venkatraman and Suresh Kumar Rayala

    Citation: Journal of Nanobiotechnology 2020 18:74

    Content type: Research

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  37. Dual inhibitors of the 5-lipoxygenase-activating protein (FLAP) and the microsomal prostaglandin E2 synthase-1 (mPGES-1) may exert better anti-inflammatory efficacy and lower risks of adverse effects versus non-s...

    Authors: Blerina Shkodra-Pula, Christian Kretzer, Paul M. Jordan, Paul Klemm, Andreas Koeberle, David Pretzel, Erden Banoglu, Stefan Lorkowski, Maria Wallert, Stephanie Höppener, Steffi Stumpf, Antje Vollrath, Stephanie Schubert, Oliver Werz and Ulrich S. Schubert

    Citation: Journal of Nanobiotechnology 2020 18:73

    Content type: Research

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  38. Spinal cord injury (SCI) has a very disabling central nervous system impact but currently lacks effective treatment. Bone marrow-derived macrophages (BMDMs) are recruited to the injured area after SCI and part...

    Authors: Jiaxing Wang, Yuluo Rong, Chengyue Ji, Chengtang Lv, Dongdong Jiang, Xuhui Ge, Fangyi Gong, Pengyu Tang, Weihua Cai, Wei Liu and Jin Fan

    Citation: Journal of Nanobiotechnology 2020 18:72

    Content type: Research

    Published on:

  39. Although many therapeutic strategies for Alzheimer’s disease (AD) have been explored, these strategies are seldom used in the clinic. Therefore, AD therapeutic research is still urgently needed. One major chal...

    Authors: Chunhong Gao, Xiaoyang Chu, Wei Gong, Jinpeng Zheng, Xiangyang Xie, Yuli Wang, Meiyan Yang, Zhiping Li, Chunsheng Gao and Yang Yang

    Citation: Journal of Nanobiotechnology 2020 18:71

    Content type: Research

    Published on:

  40. The most convenient circulating tumor cells (CTCs) identification method is direct analysis of cells under bright field microscopy by which CTCs can be comprehensive studied based on morphology, phenotype or e...

    Authors: Shuibing Wang, Shaoli Hong, Shijia Cai, Jia Lei, Jinyao Chen, Nangang Zhang, Zhao Ai, Kan Liu and Man Tang

    Citation: Journal of Nanobiotechnology 2020 18:70

    Content type: Research

    Published on:

  41. Cell-bound membrane vesicles (CBMVs) are a type of membrane vesicles different from the well-known extracellular vesicles (EVs). In recent years, the applications of EVs as drug delivery systems have been stud...

    Authors: Yang Zhang, Yang Liu, Wendiao Zhang, Qisheng Tang, Yun Zhou, Yuanfang Li, Tong Rong, Huaying Wang and Yong Chen

    Citation: Journal of Nanobiotechnology 2020 18:69

    Content type: Research

    Published on:

  42. Enhancing angiogenesis is critical for accelerating wound healing. Application of different types of exosomes (Exos) to promote angiogenesis represents a novel strategy for enhanced wound repair. Saliva is kno...

    Authors: Bobin Mi, Lang Chen, Yuan Xiong, Chenchen Yan, Hang Xue, Adriana C. Panayi, Jing Liu, Liangcong Hu, Yiqiang Hu, Faqi Cao, Yun Sun, Wu Zhou and Guohui Liu

    Citation: Journal of Nanobiotechnology 2020 18:68

    Content type: Research

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  43. Exenatide is an insulinotropic peptide drug for type 2 diabetes treatment with low risk of hypoglycemia, and is administrated by subcutaneous injection. Oral administration is the most preferred route for life...

    Authors: Xiaoyan Bao, Kang Qian and Ping Yao

    Citation: Journal of Nanobiotechnology 2020 18:67

    Content type: Research

    Published on:

  44. Osteoblast differentiation is a vital process for fracture healing, and exosomes are nanosized membrane vesicles that can deliver therapeutic drugs easily and safely. Macrophages participate in the regulation ...

    Authors: Yuan Xiong, Lang Chen, Chenchen Yan, Wu Zhou, Tao Yu, Yun Sun, Faqi Cao, Hang Xue, Yiqiang Hu, Dong Chen, Bobin Mi and Guohui Liu

    Citation: Journal of Nanobiotechnology 2020 18:66

    Content type: Research

    Published on:

  45. Nanoparticle based gene delivery systems holds great promise. Superparamagnetic iron oxide nanoparticles (SPIONs) are being heavily investigated due to good biocompatibility and added diagnostic potential, ren...

    Authors: Ozlem Unal, Yunus Akkoc, Muhammed Kocak, Esra Nalbat, Asiye Isin Dogan-Ekici, Havva Yagci Acar and Devrim Gozuacik

    Citation: Journal of Nanobiotechnology 2020 18:65

    Content type: Research

    Published on:

  46. The primary strategy to repair peripheral nerve injuries is to bridge the lesions by promoting axon regeneration. Thus, the ability to direct and manipulate neuronal cell axon regeneration has been one of the ...

    Authors: Yang Wang, Binxi Li, Hao Xu, Shulin Du, Ting Liu, Jingyan Ren, Jiayi Zhang, Hao Zhang, Yi Liu and Laijin Lu

    Citation: Journal of Nanobiotechnology 2020 18:64

    Content type: Research

    Published on:

  47. Helicobacter pylori (H. pylori) infect more than half of the world population, and they cause different serious diseases such as gastric carcinomas. This study aims to design a vaccine on the basis of cagW agains...

    Authors: Mohammad Chehelgerdi and Abbas Doosti

    Citation: Journal of Nanobiotechnology 2020 18:63

    Content type: Research

    Published on:

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