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  1. The prevalence of viral infectious diseases has become a serious threat to public safety, economic and social development. Vaccines have been served as the most effective platform to prevent virus transmission...

    Authors: Jian Huo, Angke Zhang, Shuqi Wang, Hanghang Cheng, Daopeng Fan, Ran Huang, Yanan Wang, Bo Wan, Gaiping Zhang and Hua He
    Citation: Journal of Nanobiotechnology 2022 20:514
  2. The discovery of a potent photosensitizer with desirable immunogenic cell death (ICD) ability can prominently enhance antitumor immunity in photodynamic therapy (PDT). However, majority of commercially-availab...

    Authors: Hong Wang, Guoxin Jing, Jintong Niu, Li Yang, Youyuan Li, Yi Gao, Huichao Wang, Xiaorong Xu, Yechang Qian and Shilong Wang
    Citation: Journal of Nanobiotechnology 2022 20:513
  3. Reversing the immunosuppressive tumor microenvironment (TME) in the tumor is widely deemed to be an effective strategy to improve immune therapy. In particular, the redox balance in TME needs to be well contro...

    Authors: Zhiheng Zeng, Changhui Fu, Xiaohan Sun, Meng Niu, Xiangling Ren, Longfei Tan, Qiong Wu, Zhongbing Huang and Xianwei Meng
    Citation: Journal of Nanobiotechnology 2022 20:512
  4. Inherited Retinal Diseases (IRDs) are considered one of the leading causes of blindness worldwide. However, the majority of them still lack a safe and effective treatment due to their complexity and genetic he...

    Authors: Yueh Chien, Yu-Jer Hsiao, Shih-Jie Chou, Ting-Yi Lin, Aliaksandr A. Yarmishyn, Wei-Yi Lai, Meng-Shiue Lee, Yi-Ying Lin, Tzu-Wei Lin, De-Kuang Hwang, Tai-Chi Lin, Shih-Hwa Chiou, Shih-Jen Chen and Yi-Ping Yang
    Citation: Journal of Nanobiotechnology 2022 20:511
  5. Nanotopographical cues of bone implant surface has direct influences on various cell types during the establishment of osseointegration, a prerequisite of implant bear-loading. Given the important roles of mon...

    Authors: Yide He, Yuanxue Gao, Qianli Ma, Xige Zhang, Yumei Zhang and Wen Song
    Citation: Journal of Nanobiotechnology 2022 20:510
  6. Norcantharidin (NCTD) is a demethylated derivative of cantharidin (CTD), the main anticancer active ingredient isolated from traditional Chinese medicine Mylabris. NCTD has been approved by the State Food and ...

    Authors: Bing-Tao Zhai, Jing Sun, Ya-Jun Shi, Xiao-Fei Zhang, Jun-Bo Zou, Jiang-Xue Cheng, Yu Fan, Dong-Yan Guo and Huan Tian
    Citation: Journal of Nanobiotechnology 2022 20:509
  7. Introducing oxygen-vacancy into the surface of the non-enzymatic sensor is supposed to be an effective way to improve inherently low catalytic activity and specificity of non-enzymatic sensors. In this work, C...

    Authors: Chen Zhao, Xiaoying Tang, Jinge Zhao, Jie Cao, Zhenqi Jiang and Jieling Qin
    Citation: Journal of Nanobiotechnology 2022 20:507
  8. Macrophages participate in many links in the pathological process of atherosclerosis (AS) and the regulation of influence of macrophages at the molecular level might be a new avenue for AS treatment. For this ...

    Authors: Xuan Sha, Yue Dai, Lijuan Chong, Min Wei, Mengyuan Xing, Chun Zhang and Jingjing Li
    Citation: Journal of Nanobiotechnology 2022 20:506
  9. Acute kidney injury (AKI) is one of the most common severe complications among hospitalized patients. In the absence of specific drugs to treat AKI, hemodialysis remains the primary clinical treatment for AKI ...

    Authors: Yuanpeng Nie, Liying Wang, Xinru You, Xiaohua Wang, Jun Wu and Zhihua Zheng
    Citation: Journal of Nanobiotechnology 2022 20:505
  10. Cisplatin (CDDP) is a well-known platinum-based drug used in the treatment of various malignancies. However, the widespread side effects that this drug leaves on normal tissues make its use limited. Since cisp...

    Authors: Maryam Davoudi, Yasaman Jadidi, Kiana Moayedi, Vida Farrokhi and Reza Afrisham
    Citation: Journal of Nanobiotechnology 2022 20:504
  11. The profiling of small extracellular vesicle-associated microRNAs (sEV-miRNAs) plays a vital role in cancer diagnosis and monitoring. However, detecting sEV-miRNAs with low expression in clinical samples remai...

    Authors: Ye Zhang, Wenbin Li, Tingting Ji, Shihua Luo, Jiuxiang Qiu, Bo Situ, Bo Li, Xiaohe Zhang, Tiange Zhang, Wen Wang, Yunju Xiao, Lei Zheng and Xiaohui Yan
    Citation: Journal of Nanobiotechnology 2022 20:503
  12. Dental caries is the major biofilm-mediated oral disease in the world. The main treatment to restore caries lesions consists of the use of adhesive resin composites due to their good properties. However, the p...

    Authors: Marta López-Ruiz, Francisco Navas, Paloma Fernández-García, Samuel Martínez-Erro, Mª Victoria Fuentes, Isabel Giráldez, Laura Ceballos, Carmen Mª Ferrer-Luque, Matilde Ruiz-Linares, Victoria Morales, Raúl Sanz and Rafael A. García-Muñoz
    Citation: Journal of Nanobiotechnology 2022 20:502
  13. Recent efforts in designing nanomaterials to deliver potential therapeutics to the targeted site are overwhelming and palpable. Engineering nanomaterials to deliver biological molecules to exert desirable phys...

    Authors: Ashish Ranjan Sharma, Yeon-Hee Lee, Altanzul Bat-Ulzii, Manojit Bhattacharya, Chiranjib Chakraborty and Sang-Soo Lee
    Citation: Journal of Nanobiotechnology 2022 20:501
  14. As one kind of aggressive cancer, triple-negative breast cancer (TNBC) has become one of the major causes of women mortality worldwide. Recently, combinational chemo-PDT therapy based on nanomaterials has been...

    Authors: Zhihong Zeng, Zhou Wang, Simin Chen, Chang Xiao, Minzhuo Liu, Jie Zhang, Jialong Fan, Yanzhong Zhao and Bin Liu
    Citation: Journal of Nanobiotechnology 2022 20:500
  15. Gene transfection was supposed to be the most promising technology to overcome the vast majority of diseases and it has been popularly reported in clinical applications of gene therapy. In spite of the rapid d...

    Authors: Yongtao Wang, Nana Wang, Yingjun Yang, Yazhou Chen and Zhengguo Zhang
    Citation: Journal of Nanobiotechnology 2022 20:499
  16. The lack of a satisfactory strategy for postoperative pain management significantly impairs the quality of life for many patients. However, existing nanoplatforms cannot provide a longer duration of nerve bloc...

    Authors: Bin Qiao, Xinye Song, Weiyi Zhang, Ming Xu, Bowen Zhuang, Wei Li, Huanling Guo, Wenxin Wu, Guangliang Huang, Minru Zhang, Xiaoyan Xie, Nan Zhang, Yong Luan and Chunyang Zhang
    Citation: Journal of Nanobiotechnology 2022 20:498
  17. Reactive oxygen/nitrogen species (ROS/RNS) are formed during normal cellular metabolism and contribute to its regulation, while many pathological processes are associated with ROS/RNS imbalances. Modern method...

    Authors: Tatiana Abakumova, Alexander Vaneev, Victor Naumenko, Arina Shokhina, Vsevolod Belousov, Arsen Mikaelyan, Kamilla Balysheva, Peter Gorelkin, Alexander Erofeev and Timofei Zatsepin
    Citation: Journal of Nanobiotechnology 2022 20:497
  18. Ocular diseases are increasingly influencing people’s quality of life. Complicated inflammatory mechanisms involved in the pathogenic process of ocular diseases make inflammation-targeting treatment a potentia...

    Authors: Lianfei Fang, Jin Liu, Zeyang Liu and Huifang Zhou
    Citation: Journal of Nanobiotechnology 2022 20:496
  19. Detecting physiological levels of neurotransmitters in biological samples can advance our understanding of brain disorders and lead to improved diagnostics and therapeutics. However, neurotransmitter sensors f...

    Authors: Mafalda Abrantes, Diana Rodrigues, Telma Domingues, Siva S. Nemala, Patricia Monteiro, Jérôme Borme, Pedro Alpuim and Luis Jacinto
    Citation: Journal of Nanobiotechnology 2022 20:495
  20. Carbon monoxide (CO) is an important signaling molecule participating in multiple biological functions. Previous studies have confirmed the valuable roles of CO in cancer therapies. If the CO concentration and...

    Authors: Yiyang Cong, Bo Sun, Jianlun Hu, Xiaoyang Li, Yanan Wang, Jingyi Zhang, Dongzhi Yang, Weifei Lu, Zhi Ding, Xiaofeng Wang and Hao Hong
    Citation: Journal of Nanobiotechnology 2022 20:494
  21. Virus-like particles (VLPs) are supramolecular structures composed of multiple protein subunits and resemble natural virus particles in structure and size, making them highly immunogenic materials for the deve...

    Authors: Ze-Hui Liu, Zhuo-Fan Deng, Ying Lu, Wei-Huan Fang and Fang He
    Citation: Journal of Nanobiotechnology 2022 20:493
  22. Pathogenic microorganism pollution has been a challenging public safety issue, attracting considerable scientific interest. A more problematic aspect of this phenomenon is that planktonic bacteria exacerbate b...

    Authors: Qian Wang, Qingshan Shi, Yulian Li, Shunying Lu and Xiaobao Xie
    Citation: Journal of Nanobiotechnology 2022 20:492
  23. An increasing demand for bioelectronics that interface with living systems has driven the development of materials to resolve mismatches between electronic devices and biological tissues. So far, a variety of ...

    Authors: Daiki Ando, Tetsuhiko F. Teshima, Francisco Zurita, Hu Peng, Kota Ogura, Kenji Kondo, Lennart Weiß, Ayumi Hirano-Iwata, Markus Becherer, Joe Alexander and Bernhard Wolfrum
    Citation: Journal of Nanobiotechnology 2022 20:491
  24. Deficient deposition of X-rays and strong capacity of repairing damage DNA of cancer cells limit the effect of radiation therapy (RT). Herein, we synthesize CsLu2F7 nanoparticles with lactic acid (LA) ligands (Cs...

    Authors: Hu Liu, Han Wang, Dalong Ni and Youjia Xu
    Citation: Journal of Nanobiotechnology 2022 20:490
  25. The liver is an important organ in the human body and performs many functions, such as digestion, detoxification, metabolism, immune responses, and vitamin and mineral storage. Therefore, disorders of liver fu...

    Authors: Feixiang Luo, Ying Yu, Mingqian Li, Yuguo Chen, Peng Zhang, Chunsheng Xiao and Guoyue Lv
    Citation: Journal of Nanobiotechnology 2022 20:488
  26. Circular RNA (circRNA) is a type of stable non-coding RNA that modifies macrophage inflammation by sponging micro RNAs (miRNAs), binding to RNA-binding proteins, and undergoing translation into peptides. Activ...

    Authors: Yuhua Gao, Ningning Mi, Ying Zhang, Xiangchen Li, Weijun Guan and Chunyu Bai
    Citation: Journal of Nanobiotechnology 2022 20:487
  27. As the most common subtype in lung cancer, the precise and efficient treatment for non-small cell lung cancer (NSCLC) remains an outstanding challenge owing to early metastasis and poor prognosis. Chemotherapy...

    Authors: Ning Wang, Chang Yu, Tingting Xu, Dan Yao, Lingye Zhu, Zhifa Shen and Xiaoying Huang
    Citation: Journal of Nanobiotechnology 2022 20:486
  28. Currently, tumor treatments are characterized by intelligence, diversity and personalization, but the therapeutic reagents used are often limited in clinical efficacy due to problems with water solubility, tar...

    Authors: Luyao Tian, Xia Li, Haixia Ji, Qing Yu, Mingjuan Yang, Lanping Guo, Luqi Huang and Wenyuan Gao
    Citation: Journal of Nanobiotechnology 2022 20:485
  29. Nanomaterial-based phototherapy has become an important research direction for cancer therapy, but it still to face some obstacles, such as the toxic side effects and low target specificity. The biomimetic syn...

    Authors: Peng He, Guozheng Yang, Danzhu Zhu, Hao Kong, Yendry Regina Corrales-Ureña, Lucio Colombi Ciacchi and Gang Wei
    Citation: Journal of Nanobiotechnology 2022 20:483
  30. Inspired by nature, green chemistry uses various biomolecules, such as proteins, as reducing agents to synthesize metallic nanostructures. This methodology provides an alternative route to conventional harsh s...

    Authors: Roman Nudelman, Hashim Alhmoud, Bahman Delalat, Ishdeep Kaur, Anastasia Vitkin, Laure Bourgeois, Ilan Goldfarb, Anna Cifuentes-Rius, Nicolas H. Voelcker and Shachar Richter
    Citation: Journal of Nanobiotechnology 2022 20:482
  31. Currently available anti-leukemia drugs have shown limited success in the treatment of acute myeloid leukemia (AML) due to their poor access to bone marrow niche supporting leukemic cell proliferation.

    Authors: Ki Hyun Bae, Fritz Lai, Jamie Mong, Akiko Niibori-Nambu, Kiat Hwa Chan, Zhisheng Her, Motomi Osato, Min-Han Tan, Qingfeng Chen and Motoichi Kurisawa
    Citation: Journal of Nanobiotechnology 2022 20:481
  32. Precision medicine is the ultimate goal for current disease therapies, including tumor and infection. The lack of specific targeted drugs for liver cancer and the lack of specific anti-infective drugs in the t...

    Authors: Yiyin Zhang, Yiling Li, Qiming Xia, Yirun Li, Shengxi Jin, Qijiang Mao, Chao Liu, Xiaoxiao Fan and Hui Lin
    Citation: Journal of Nanobiotechnology 2022 20:480
  33. Accumulating evidence suggests that osteoclastogenesis and angiogenesis in subchondral bone are critical destructive factors in the initiation and progression of osteoarthritis (OA). Herein, methoxypolyethylen...

    Authors: Zhikai Wu, Kai Yuan, Qian Zhang, Jiong Jiong Guo, Huilin Yang and Feng Zhou
    Citation: Journal of Nanobiotechnology 2022 20:479
  34. A film with elaborate microstructures that offers biomimetic properties and multi functionalities is highly desired in wound healing. Here, we develop an aligned hydrogel fiber film integrated with multi-activ...

    Authors: Boda Wu, Jintao Yang, Yan Zu, Junjie Chi and Keqing Shi
    Citation: Journal of Nanobiotechnology 2022 20:478
  35. Swine influenza A viruses (SwIAVs) pose an economic and pandemic threat, and development of novel effective vaccines is of critical significance. We evaluated the performance of split swine influenza A virus (...

    Authors: V. Patil, J. F. Hernandez-Franco, G. Yadagiri, D. Bugybayeva, S. Dolatyabi, N. Feliciano-Ruiz, J. Schrock, J. Hanson, J. Ngunjiri, H. HogenEsch and G. J. Renukaradhya
    Citation: Journal of Nanobiotechnology 2022 20:477
  36. Multidrug resistance (MDR) has been restricting the efficacy of chemotherapy, which mainly include pump resistance and non-pump resistance. In order to fight overall MDR, a novel targeted gene/drug co-deliver ...

    Authors: Changduo Wang, Zhipeng Li, Ping Xu, Lisa Xu, Shangcong Han and Yong Sun
    Citation: Journal of Nanobiotechnology 2022 20:476
  37. Phototherapy is a conducive and non-invasive strategy for cancer therapy under light irradiation. Inspiringly, fluorescence imaging in the second near-infrared window (NIR-II, 1000–1700 nm) holds a great promi...

    Authors: Sha Yang, Gui-long Wu, Na Li, Minghui Wang, Peixian Wu, Yuxuan He, Wei Zhou, Hao Xiao, Xiaofeng Tan, Li Tang and Qinglai Yang
    Citation: Journal of Nanobiotechnology 2022 20:475
  38. Chronic metabolic diseases such as diabetes are characterized by delayed wound healing and a dysregulation of the inflammatory phase of wound repair. Our study focuses on changes in the payload of extracellula...

    Authors: Dong Jun Park, Erika Duggan, Kayla Ho, Robert A. Dorschner, Marek Dobke, John P. Nolan and Brian P. Eliceiri
    Citation: Journal of Nanobiotechnology 2022 20:474
  39. Platinum nanoparticles have been demonstrated to have excellent anticancer properties. However, because of the lack of specificity they must be delivered to the tumor in amounts sufficient to reach the desired...

    Authors: María Sancho-Albero, Ana Martín-Pardillos, Lluís Lujan, Víctor Sebastian, Jesús Santamaria and Pilar Martín-Duque
    Citation: Journal of Nanobiotechnology 2022 20:473
  40. Metastasis and chemical resistance are the most serious problems in the treatment of highly aggressive uveal melanoma (UM). The newly identified lncRNA OUM1 is overexpressed in UM, functions as a catalyst and reg...

    Authors: Yue Li, Fang Li, Hui Pan, Xiaolin Huang, Jie Yu, Xueru Liu, Qinghao Zhang, Caiwen Xiao, He Zhang and Leilei Zhang
    Citation: Journal of Nanobiotechnology 2022 20:472
  41. Ovarian cancer is a highly fatal gynecologic malignancy worldwide. Chemotherapy remains the primary modality both for primary and maintenance treatments of ovarian cancer. However, the progress in developing c...

    Authors: Guang Li, Mingjian Ling, Kunyi Yu, Wei Yang, Qiwen Liu, Lijuan He, Xuzi Cai, Min Zhong, Ziyi Mai, Rui Sun, Yuanling Xiao, Zhiqiang Yu and Xuefeng Wang
    Citation: Journal of Nanobiotechnology 2022 20:471
  42. Pathogenic dental plaque biofilms are universal and harmful, which can result in oral infections and systemic diseases. Many conventional therapeutic methods have proven insufficient or ineffective against pla...

    Authors: Yangheng Zhang, Rixin Chen, Yuxian Wang, Peng Wang, Jiajie Pu, Xiaoqiang Xu, Faming Chen, Ling Jiang, Qing Jiang and Fuhua Yan
    Citation: Journal of Nanobiotechnology 2022 20:470
  43. Osteoarthritis (OA) is a common joint disorder worldwide which causes great health and economic burden. However, there remains an unmet goal to develop an effective therapeutic method to prevent or delay OA. C...

    Authors: Yu Jin, Qing Zhang, Xing Qin, Zhen Liu, Zhenxia Li, Xiaoxia Zhong, Lunguo Xia, Jie He and Bing Fang
    Citation: Journal of Nanobiotechnology 2022 20:469
  44. The hypoimmunogenicity of tumors is one of the main bottlenecks of cancer immunotherapy. Enhancing tumor immunogenicity can improve the efficacy of tumor immunotherapy by increasing antigen exposure and presen...

    Authors: Xiaowen Zhong, Chenyang Li, Guangzong Zhao, Mengmeng Li, Shuning Chen, Yang Cao, Qi Wang, Jiangchuan Sun, Shenyin Zhu and Shufang Chang
    Citation: Journal of Nanobiotechnology 2022 20:468
  45. In 2020, nearly 20 million peoples got cancer and nearly 10 million peoples died of cancer, indicating the cancer remains a great threat to human health and life. New therapies are still in urgent demand. We h...

    Authors: Tao Luo, Yile Wang and Jinke Wang
    Citation: Journal of Nanobiotechnology 2022 20:467
  46. Tumor phototheranostics holds a great promise on account of its high spatiotemporal resolution, tumor-specificity, and noninvasiveness. However, physical limitation of light penetration and “always on” propert...

    Authors: Chaoyi Chen, Yuwen Chen, Lulu Zhang, Xuanhao Wang, Qingshuang Tang, Yan Luo, Yuan Wang, Cheng Ma and Xiaolong Liang
    Citation: Journal of Nanobiotechnology 2022 20:466
  47. Tissue engineering of hair follicles (HFs) has enormous potential for hair loss treatment. However, certain challenges remain, including weakening of the dermal papilla cell (DPC) viability, proliferation, and...

    Authors: Yufan Zhang, Panjing Yin, Junfei Huang, Lunan Yang, Zhen Liu, Danlan Fu, Zhiqi Hu, Wenhua Huang and Yong Miao
    Citation: Journal of Nanobiotechnology 2022 20:465

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