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  1. Content type: Research

    The conventional approaches to assess the potential cytotoxic effects of nanomaterials (NMs) mainly rely on in vitro biochemical assays. These assays are strongly dependent on the properties of the nanomateria...

    Authors: Homero F. Pastrana, Alexander X. Cartagena-Rivera, Arvind Raman and Alba Ávila

    Citation: Journal of Nanobiotechnology 2019 17:32

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  2. Content type: Research

    Circulating tumor cells (CTCs) comprise the high metastatic potential population of cancer cells in the blood circulation of humans; they have become the established biomarkers for cancer diagnosis, individual...

    Authors: Chia-Cheng Yu, Yi-Wen Chen, Po-Ying Yeh, Yu-Sheng Hsiao, Wei-Ting Lin, Chiung-Wen Kuo, Di-Yen Chueh, Yun-Wen You, Jing-Jong Shyue, Ying-Chih Chang and Peilin Chen

    Citation: Journal of Nanobiotechnology 2019 17:31

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  3. Content type: Research

    Malignant glioma is the most common and deadliest brain cancer due to the obstacle from indistinct tumor margins for surgical excision and blood brain barrier (BBB) for chemotherapy. Here, we designed and prep...

    Authors: Lingzhou Zhao, Yujie Li, Jingyi Zhu, Na Sun, Ningning Song, Yan Xing, He Huang and Jinhua Zhao

    Citation: Journal of Nanobiotechnology 2019 17:30

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  4. Content type: Research

    Accumulating evidence shows that microRNA-210 (miR-210) holds great promise to improve angiogenesis for brain tissue repair after cerebral ischemia. However, safe and efficient delivery of miR-210 via intraven...

    Authors: Huixin Zhang, Jin Wu, Jiahuan Wu, Qi Fan, Jingchao Zhou, Junwen Wu, Sichen Liu, Jie Zang, Jinhai Ye, Ming Xiao, Tian Tian and Jun Gao

    Citation: Journal of Nanobiotechnology 2019 17:29

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  5. Content type: Correction

    Following publication of this article [1] we found a typographical error in the results reported in the abstract. The corrected sentences should read as below:

    Authors: Dennis Kreft, Ying Wang, Michael Rattay, Katja Toensing and Dario Anselmetti

    Citation: Journal of Nanobiotechnology 2019 17:28

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    The original article was published in Journal of Nanobiotechnology 2018 16:56

  6. Content type: Research

    Theranostics application of superparamagnetic nanoparticles based on magnetite and maghemite is impeded by their toxicity. The use of additional protective shells significantly reduced the magnetic properties ...

    Authors: Anastasiia Garanina, Igor Kireev, Oxana Zhironkina, Olga Strelkova, Anton Shakhov, Irina Alieva, Valery Davydov, Sankaran Murugesan, Valery Khabashesku, Alexander Majouga, Viatcheslav Agafonov and Rustem Uzbekov

    Citation: Journal of Nanobiotechnology 2019 17:27

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  7. Content type: Research

    The detection of circulating tumor cells (CTCs) is very important for cancer diagnosis. CTCs can travel from primary tumors through the circulation to form secondary tumor colonies via bloodstream extravasatio...

    Authors: Chiung Wen Kuo, Di-Yen Chueh and Peilin Chen

    Citation: Journal of Nanobiotechnology 2019 17:26

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  8. Content type: Research

    A cationic liposome-PEG-PEI complex (LPPC) was employed as a carrier for achieving targeted delivery of drug to human epidermal growth factor receptor-2 (HER2/neu)-expressing breast cancer cells. LPPC can be e...

    Authors: Yu-Ling Lin, Nu-Man Tsai, Chia-Hung Chen, Yen-Ku Liu, Chung-Jen Lee, Yi-Lin Chan, Yu-Shan Wang, Yuan-Ching Chang, Chi-Hsin Lin, Tse-Hung Huang, Chao Ching Wang, Kwan-Hwa Chi and Kuang-Wen Liao

    Citation: Journal of Nanobiotechnology 2019 17:25

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  9. Content type: Research

    Silica nanoparticles (SiNPs) are widely used for biosensing and diagnostics, and for the targeted delivery of therapeutic agents. Safety concerns about the biomedical and clinical applications of SiNPs have be...

    Authors: Kyungmin Lee, Jangwook Lee, Minjeong Kwak, Young-Lai Cho, Byungtae Hwang, Min Ji Cho, Na Geum Lee, Jongjin Park, Sang-Hyun Lee, Jong-Gil Park, Yeon-Gu Kim, Jang-Seong Kim, Tae-Su Han, Hyun-Soo Cho, Young-Jun Park, Seon-Jin Lee…

    Citation: Journal of Nanobiotechnology 2019 17:24

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  10. Content type: Research

    In recent years, multifunctional theranostic nanoparticles have been fabricated by integrating imaging and therapeutic moieties into one single nano-formulations. However, Complexity of production and safety i...

    Authors: Xianlei Li, Xuan Wang, Caiyan Zhao, Leihou Shao, Jianqing Lu, Yujia Tong, Long Chen, Xinyue Cui, Huiling Sun, Junxing Liu, Mingjun Li, Xiongwei Deng and Yan Wu

    Citation: Journal of Nanobiotechnology 2019 17:23

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  11. Content type: Research

    Human plasma gelsolin (pGSN) is a multifunctional actin-binding protein involved in a variety of biological processes, including neutralization of pro-inflammatory molecules such as lipopolysaccharide (LPS) an...

    Authors: Ewelina Piktel, Urszula Wnorowska, Mateusz Cieśluk, Piotr Deptula, Katarzyna Pogoda, Iwona Misztalewska-Turkowicz, Paulina Paprocka, Katarzyna Niemirowicz-Laskowska, Agnieszka Z. Wilczewska, Paul A. Janmey and Robert Bucki

    Citation: Journal of Nanobiotechnology 2019 17:22

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  12. Content type: Methodology

    Emerging concepts for designing innovative drugs (i.e., novel generations of antimicrobials) frequently include nanostructures, new materials, and nanoparticles (NPs). Along with numerous advantages, NPs bring...

    Authors: Marija Vukomanovic and Eduard Torrents

    Citation: Journal of Nanobiotechnology 2019 17:21

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  13. Content type: Research

    A growing body of evidence shows that indoor concentrations of airborne particles are often higher than is typically encountered outdoors. Since exposure to indoor PM2.5 is thought to be associated with cardio...

    Authors: Yan Li, Chuanlin Hu, Pengcheng Wang, Yan Liu, Luyang Wang, Qingmeng Pi, Zhiyong Gong, Xu Yang, Michael Mak and Yang Wu

    Citation: Journal of Nanobiotechnology 2019 17:20

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  14. Content type: Research

    Protein-based Cas9 in vivo gene editing therapeutics have practical limitations owing to their instability and low efficacy. To overcome these obstacles and improve stability, we designed a nanocarrier primari...

    Authors: Eun Yi Cho, Jee-Yeon Ryu, Han A. Reum Lee, Shin Hee Hong, Hye Sun Park, Kwan Soo Hong, Sang-Gyu Park, Hong Pyo Kim and Tae-Jong Yoon

    Citation: Journal of Nanobiotechnology 2019 17:19

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  15. Content type: Research

    Cyclosporin A (CsA) is a promising therapeutic drug for myocardial ischemia reperfusion injury (MI/RI) because of its definite inhibition to the opening of mitochondrial permeability transition pore (mPTP). Ho...

    Authors: Chang-xiong Zhang, Ying Cheng, Dao-zhou Liu, Miao Liu, Han Cui, Bang-le Zhang, Qi-bing Mei and Si-yuan Zhou

    Citation: Journal of Nanobiotechnology 2019 17:18

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  16. Content type: Research

    Dental caries is a recognized worldwide public health problem. Despite being one of the most effective strategies against dental caries, the excessive use of fluorine may result in a potential risk of developi...

    Authors: Maurizio Bossù, Matteo Saccucci, Alessandro Salucci, Gianni Di Giorgio, Erika Bruni, Daniela Uccelletti, Maria Sabrina Sarto, Giuseppe Familiari, Michela Relucenti and Antonella Polimeni

    Citation: Journal of Nanobiotechnology 2019 17:17

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  17. Content type: Research

    Exosomes are considered key elements for communication between cells, but very little is known about the mechanisms and selectivity of the transference processes involving exosomes released from different cells.

    Authors: María Sancho-Albero, Nuria Navascués, Gracia Mendoza, Víctor Sebastián, Manuel Arruebo, Pilar Martín-Duque and Jesús Santamaría

    Citation: Journal of Nanobiotechnology 2019 17:16

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  18. Content type: Research

    Infectious diseases are still a leading cause of death and, with the emergence of drug resistance, pose a great threat to human health. New drugs and strategies are thus urgently needed to improve treatment ef...

    Authors: Juan Manuel Coya, Laura De Matteis, Alexandre Giraud-Gatineau, Anne Biton, Inés Serrano-Sevilla, Anne Danckaert, Marie-Agnès Dillies, Brigitte Gicquel, Jesus M. De la Fuente and Ludovic Tailleux

    Citation: Journal of Nanobiotechnology 2019 17:15

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  19. Content type: Research

    T lymphocytes are highly dynamic elements of the immune system with a tightly regulated migration. T cell-based transfer therapies are promising therapeutic approaches which in vivo efficacy is often limited b...

    Authors: Laura Sanz-Ortega, José M. Rojas, Ana Marcos, Yadileiny Portilla, Jens V. Stein and Domingo F. Barber

    Citation: Journal of Nanobiotechnology 2019 17:14

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  20. Content type: Research

    Rotavirus is the leading cause of severe dehydrating diarrhea in young children and the inner capsid protein VP6 is a potential vaccine candidate that can induce cross-protective immune responses against diffe...

    Authors: Zhipeng Li, Kuiqing Cui, Hong Wang, Fuhang Liu, Kongwei Huang, Zhaojun Duan, Fengchao Wang, Deshun Shi and Qingyou Liu

    Citation: Journal of Nanobiotechnology 2019 17:13

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  21. Content type: Research

    Frequent injection of high-dose methylprednisolone (MP) is used to treat spinal cord injury (SCI), but free MP is associated with various side effects and its water solubility is low, limiting potential dosing...

    Authors: Yan Lin, Chunhong Li, Jian Li, Ruolan Deng, Juan Huang, Qinglian Zhang, Jiayao Lyu, Na Hao and Zhirong Zhong

    Citation: Journal of Nanobiotechnology 2019 17:12

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  22. Content type: Research

    We developed a non-viral vector, a combination of HIV-1 Tat peptide modified with histidine and cysteine (mTat) and polyethylenimine, jetPEI (PEI), displaying the high efficiency of plasmid DNA transfection wi...

    Authors: Hironori Kasai, Kenji Inoue, Kentaro Imamura, Carlo Yuvienco, Jin K. Montclare and Seiichi Yamano

    Citation: Journal of Nanobiotechnology 2019 17:11

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  23. Content type: Research

    Osteoporosis is a bone-incapacitating malady and it is characterized by obvious bone mass loss and bone microarchitecture deterioration. Current treatments for osteoporosis have many limitations, including the...

    Authors: Xiaoduan Sun, Jun Wei, Jiayao Lyu, Tierong Bian, Zhongbing Liu, Juan Huang, Fengjuan Pi, Chunhong Li and Zhirong Zhong

    Citation: Journal of Nanobiotechnology 2019 17:10

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  24. Content type: Research

    Development of multidrug resistance (MDR) is a major burden of successful chemotherapy, therefore, novel approaches to defeat MDR are imperative. Although the remarkable anti-cancer propensity of silver nanopa...

    Authors: Mohana Krishna Gopisetty, Dávid Kovács, Nóra Igaz, Andrea Rónavári, Péter Bélteky, Zsolt Rázga, Viktória Venglovecz, Bálint Csoboz, Imre Miklós Boros, Zoltán Kónya and Mónika Kiricsi

    Citation: Journal of Nanobiotechnology 2019 17:9

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  25. Content type: Research

    Leading to more and more deaths and disabilities, stroke has become a serious threat to human health. What’s more, few effective drugs are available in clinic till now.

    Authors: Xiangrui Yang, Lanxi Xu, Juan Zhou, Yunlong Ge, Shichao Wu, Junxiong Huang, Ying Li, Maoshu Zhu, Xin Jin and Lichao Yang

    Citation: Journal of Nanobiotechnology 2019 17:8

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  26. Content type: Research

    The rationale of this study is to combine the merits of both albumin nanoparticles and quantum dots (QDs) in improved drug tumor accumulation and strong fluorescence imaging capability into one carrier. Howeve...

    Authors: Dina G. Zayed, Shaker M. Ebrahim, Maged W. Helmy, Sherine N. Khattab, Mohammed Bahey-El-Din, Jia-You Fang, Kadria A. Elkhodairy and Ahmed O. Elzoghby

    Citation: Journal of Nanobiotechnology 2019 17:7

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  27. Content type: Research

    Helicobacter pylori (H. pylori) infection remains a global public health issue, especially in Asia. Due to the emergence of antibiotic-resistant strains and the complexity of H. pylori infection, conventional vac...

    Authors: Yun Yang, Li Chen, Hong-wu Sun, Hong Guo, Zhen Song, Ying You, Liu-yang Yang, Ya-nan Tong, Ji-ning Gao, Hao Zeng, Wu-chen Yang and Quan-ming Zou

    Citation: Journal of Nanobiotechnology 2019 17:6

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  28. Content type: Retraction Note

    The Editors have retracted this article [1] because Figs. 6a and 6c have been used in three other publications to represent scanning electron micrographs of different nanoparticles [2–4]. The data reported in ...

    Authors: Abolfazl Akbarzadeh, Mohammad Samiei, Sang Woo Joo, Maryam Anzaby, Younes Hanifehpour, Hamid Tayefi Nasrabadi and Soodabeh Davaran

    Citation: Journal of Nanobiotechnology 2019 17:5

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    The original article was published in Journal of Nanobiotechnology 2012 10:46

  29. Content type: Correction

    After publication of the original article [1], an error was noted in the author affiliation. Lin Long is also affiliated to the College of Opto-electronic Engineering, Zaozhuang University, Zaozhuang, China, w...

    Authors: Lin Long, Jianbo Liu, Kaishun Lu, Tao Zhang, Yunqing Xie, Yinglu Ji and Xiaochun Wu

    Citation: Journal of Nanobiotechnology 2019 17:4

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    The original article was published in Journal of Nanobiotechnology 2018 16:46

  30. Content type: Research

    Retinal degeneration diseases affect millions of patients worldwide and lead to incurable vision loss. These diseases are caused by pathologies in the retina and underlying choroid, located in the back of the ...

    Authors: Adi Tzameret, Hadas Ketter-Katz, Victoria Edelshtain, Ifat Sher, Enav Corem-Salkmon, Itay Levy, David Last, David Guez, Yael Mardor, Shlomo Margel and Ygal Rotenstrich

    Citation: Journal of Nanobiotechnology 2019 17:3

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  31. Content type: Research

    Previous studies have demonstrated that exposure to nickel nanoparticles (Nano-Ni) causes oxidative stress and severe, persistent lung inflammation, which are strongly associated with pulmonary toxicity. Howev...

    Authors: Yiqun Mo, Mizu Jiang, Yue Zhang, Rong Wan, Jing Li, Chuan-Jian Zhong, Huangyuan Li, Shichuan Tang and Qunwei Zhang

    Citation: Journal of Nanobiotechnology 2019 17:2

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  32. Content type: Research

    Tumor-derived exosomes are gaining attention as important factors that facilitate communication between neighboring cells and manipulate cellular processes associated with cancer development or progression. Th...

    Authors: Jiyun Lim, Mihye Choi, HyungJae Lee, Young-Ho Kim, Ji-Youn Han, Eun Sook Lee and Youngnam Cho

    Citation: Journal of Nanobiotechnology 2019 17:1

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  33. Content type: Research

    Acute lung injury (ALI) is a life-threatening clinical syndrome without effective treatment. Targeting delivery of glucocorticoid to lung shows potential efficacy for ALI based on their anti-inflammatory and a...

    Authors: Shujuan Li, Li Chen, Guokang Wang, Lexing Xu, Shanshan Hou, Ziwei Chen, Xiaoling Xu, Xiaojuan Wang, Fuhe Liu and Yong-Zhong Du

    Citation: Journal of Nanobiotechnology 2018 16:105

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  34. Content type: Research

    Recently, a combination of photodynamic therapy (PDT) and photothermal therapy (PTT) to generate reactive oxygen species (ROS) and heat to kill cancer cells, respectively has attracted considerable attention b...

    Authors: Jooran Lee, Young Hwa Lee, Chan Bae Jeong, Joon Sig Choi, Ki Soo Chang and Minjoong Yoon

    Citation: Journal of Nanobiotechnology 2018 16:104

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  35. Content type: Research

    Sorafenib is an effective clinical drug in therapy of hepatocellular carcinoma, having led to improved prognosis in hepatocellular carcinoma patients. However acquired resistance is still being encountered. So...

    Authors: Hongdan Li, Cheng Yang, Yijie Shi and Liang Zhao

    Citation: Journal of Nanobiotechnology 2018 16:103

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  36. Content type: Review

    Atomic force microscopy (AFM) allows for nanometer-scale investigation of cells and molecules. Recent advances have enabled its application in cancer research and diagnosis. The physicochemical properties of l...

    Authors: Xiangying Deng, Fang Xiong, Xiayu Li, Bo Xiang, Zheng Li, Xu Wu, Can Guo, Xiaoling Li, Yong Li, Guiyuan Li, Wei Xiong and Zhaoyang Zeng

    Citation: Journal of Nanobiotechnology 2018 16:102

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  37. Content type: Research

    We introduce a self-assembling polypeptide-based nanotube system having the ability to specifically target cancer cells. The nanotubes target the cancer cell surface through integrin engagement with the help o...

    Authors: Gitanjali Asampille, Brijesh Kumar Verma, Monalisa Swain, Abhijith Shettar, Steven A. Rosenzweig, Paturu Kondaiah and Hanudatta S. Atreya

    Citation: Journal of Nanobiotechnology 2018 16:101

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  38. Content type: Research

    Particokinetic models are important to predict the effective cellular dose, which is key to understanding the interactions of particles with biological systems. For the reliable establishment of dose–response ...

    Authors: Thomas Kowoll, Susanne Fritsch-Decker, Silvia Diabaté, Gerd Ulrich Nienhaus, Dagmar Gerthsen and Carsten Weiss

    Citation: Journal of Nanobiotechnology 2018 16:100

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  39. Content type: Research

    Cancer stem cells (CSCs) are highly proliferative and tumorigenic, which contributes to chemotherapy resistance and tumor occurrence. CSCs specific therapy may achieve excellent therapeutic effects, especially...

    Authors: Yuanyuan Li, Sanjun Shi, Yue Ming, Linli Wang, Chenwen Li, Minghe Luo, Ziwei Li, Bin Li and Jianhong Chen

    Citation: Journal of Nanobiotechnology 2018 16:99

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  40. Content type: Research

    Sustained drug delivery is a large unmet clinical need in glaucoma. Here, we incorporated a Myocardin-Related Transcription Factor/Serum Response Factor inhibitor, CCG-222740, into slow release large unilamell...

    Authors: Aristides D. Tagalakis, Shivam Madaan, Scott D. Larsen, Richard R. Neubig, Peng T. Khaw, Ian Rodrigues, Saurabh Goyal, Kin Sheng Lim and Cynthia Yu-Wai-Man

    Citation: Journal of Nanobiotechnology 2018 16:97

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  41. Content type: Research

    In orthopedic surgery, implant-associated infections are still a major problem. For the improvement of the selective therapy in the infection area, magnetic nanoparticles as drug carriers are promising when us...

    Authors: Hilke Catherina Janßen, Dawid Peter Warwas, David Dahlhaus, Jessica Meißner, Piriya Taptimthong, Manfred Kietzmann, Peter Behrens, Janin Reifenrath and Nina Angrisani

    Citation: Journal of Nanobiotechnology 2018 16:96

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  42. Content type: Review

    The need and desire to understand the environment, especially the quality of one’s local water and air, has continued to expand with the emergence of the digital age. The bottleneck in understanding the enviro...

    Authors: Marjorie R. Willner and Peter J. Vikesland

    Citation: Journal of Nanobiotechnology 2018 16:95

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  43. Content type: Research

    Modern agricultural practises rely on surfactant-based spray applications to eliminate weeds in crops. The wide spread and indiscriminate use of surfactants may result in a number of deleterious effects that a...

    Authors: Pavani P. Nadiminti, Qingtao Liu, Lavanya K. Vanjari, Yao D. Dong, Ben J. Boyd and David M. Cahill

    Citation: Journal of Nanobiotechnology 2018 16:94

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  44. Content type: Research

    Given the great benefits of artificial enzymes, a simple approach is proposed via assembling of Ni2+ with hemin for synthesis of Ni-hemin metal–organic-frameworks (Ni-hemin MOFs) mimic enzyme. The formation of th...

    Authors: Negar Alizadeh, Abdollah Salimi, Rahman Hallaj, Fardin Fathi and Farzad Soleimani

    Citation: Journal of Nanobiotechnology 2018 16:93

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  45. Content type: Research

    Atherosclerosis, a major source of cardiovascular disease, is asymptomatic for decades until the activation of thrombosis and the rupture of enlarged plaques, resulting in acute coronary syndromes and sudden c...

    Authors: Christopher Poon, Juan Gallo, Johan Joo, Timothy Chang, Manuel Bañobre-López and Eun Ji Chung

    Citation: Journal of Nanobiotechnology 2018 16:92

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  46. Content type: Research

    Microdialysis is promising technique for dynamic microbiochemical sampling from tissues. However, the application of typical aqueous perfusates to liposoluble substances is limited. In this study, a novel micr...

    Authors: Yong-Tai Zhang, Zhi Wang, Li-Na Shen, Yan-Yan Li, Ze-Hui He, Qing Xia and Nian-Ping Feng

    Citation: Journal of Nanobiotechnology 2018 16:91

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  47. Content type: Research

    In the last decade, the biosynthesis of metal nanoparticles using organisms have received more and more considerations. However, the complex composition of organisms adds up to a great barrier for the characte...

    Authors: Shichao Wu, Xiangrui Yang, Fanghong Luo, Ting Wu, Peilan Xu, Mingyuan Zou and Jianghua Yan

    Citation: Journal of Nanobiotechnology 2018 16:90

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  48. Content type: Research

    Developing an ideal wound dressing that meets the multiple demands of good biocompatibility, an appropriate porous structure, superior mechanical property and excellent antibacterial activity against drug-resi...

    Authors: Menglong Liu, Tengfei Liu, Xiwei Chen, Jiacai Yang, Jun Deng, Weifeng He, Xiaorong Zhang, Qiang Lei, Xiaohong Hu, Gaoxing Luo and Jun Wu

    Citation: Journal of Nanobiotechnology 2018 16:89

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  49. Content type: Research

    We have previously shown that intraperitoneal injection of gold nanoparticles (AuNPs, 20–30 nm) into mice, decreases high-fat diet (HFD) induced weight gain and glucose intolerance, via suppression of inflamma...

    Authors: Hui Chen, Jane P. M. Ng, David P. Bishop, Bruce K. Milthorpe and Stella M. Valenzuela

    Citation: Journal of Nanobiotechnology 2018 16:88

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