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  1. The optimal drug delivery system should be biocompatible, biodegradable, and allow the sustained release of the drug only after it reaches the target cells. Silk, as a natural polymer, is a great candidate for...

    Authors: Kamil Kucharczyk, Anna Florczak, Tomasz Deptuch, Karolina Penderecka, Katarzyna Jastrzebska, Andrzej Mackiewicz and Hanna Dams-Kozlowska

    Citation: Journal of Nanobiotechnology 2020 18:56

    Content type: Research

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  2. Psoriasis is a malignant skin disease characterized as keratinocyte hyperproliferation and aberrant differentiation. Our previous work reported that a bibenzyl compound, erianin, has a potent inhibitory effect...

    Authors: Canlong Mo, Lulu Lu, Danyang Liu and Kun Wei

    Citation: Journal of Nanobiotechnology 2020 18:55

    Content type: Research

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  3. Influenza viruses (IVs) have become increasingly resistant to antiviral drugs that target neuraminidase and matrix protein 2 due to gene mutations that alter their drug-binding target protein regions. Conseque...

    Authors: Jinyoung Kim, Minjoo Yeom, Taeksu Lee, Hyun-Ouk Kim, Woonsung Na, Aram Kang, Jong-Woo Lim, Geunseon Park, Chaewon Park, Daesub Song and Seungjoo Haam

    Citation: Journal of Nanobiotechnology 2020 18:54

    Content type: Research

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  4. Ototoxicity is one of the major side effects of platinum-based chemotherapy, especially cisplatin therapy. To date, no FDA approved agents to alleviate or prevent this ototoxicity are available. However, ototo...

    Authors: Jiayi Gu, Yuming Chen, Ling Tong, Xueling Wang, Dehong Yu and Hao Wu

    Citation: Journal of Nanobiotechnology 2020 18:53

    Content type: Research

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  5. Graphene oxide (GO) nanoparticles (NPs) have been widely applied in various fields, especially in biomedical applications. Extensive studies have suggested that GO can pass through the blood–brain barrier (BBB...

    Authors: Chao Zhang, Xiaoli Feng, Longwen He, Yaqing Zhang and Longquan Shao

    Citation: Journal of Nanobiotechnology 2020 18:52

    Content type: Research

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  6. The state-of-the-art hernia meshes, used in hospitals for hernia repair, are predominantly polymeric textile-based constructs that present high mechanical strength, but lack antimicrobial properties. Consequen...

    Authors: Antonios Keirouz, Norbert Radacsi, Qun Ren, Alex Dommann, Guido Beldi, Katharina Maniura-Weber, René M. Rossi and Giuseppino Fortunato

    Citation: Journal of Nanobiotechnology 2020 18:51

    Content type: Research

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  7. Enzalutamide (Enz) has shown limited bioavailability via oral administration. Castration-resistant prostate cancer (CRPC) is frequent among patients receiving 18–24 months of androgen deprivation therapy. The ...

    Authors: Wenjun Jiang, Jiyuan Chen, Chunai Gong, Yuanyuan Wang, Yuan Gao and Yongfang Yuan

    Citation: Journal of Nanobiotechnology 2020 18:50

    Content type: Research

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  8. Herein, a novel phototheranostic nanocomplex that is self-assembled from bovine serum albumin (BSA) and indocyanine green (ICG) is developed for enhanced near-infrared (NIR) fluorescence imaging, which benefit...

    Authors: Feifei An, Zhao Yang, Meichen Zheng, Ting Mei, Guowei Deng, Ping Guo, Yanan Li and Ruilong Sheng

    Citation: Journal of Nanobiotechnology 2020 18:49

    Content type: Research

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  9. Specific targeting ability and good cell penetration are two critical requirements of tumor-targeted delivery systems. In the present work, we developed a novel matrix metalloprotein-triggered, cell-penetratin...

    Authors: Fangyuan Guo, Qiafan Fu, Kang Zhou, Chenghao Jin, Wenchao Wu, Xugang Ji, Qinying Yan, Qingliang Yang, Danjun Wu, Aiqin Li and Gensheng Yang

    Citation: Journal of Nanobiotechnology 2020 18:48

    Content type: Research

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  10. Transplantation of mesenchymal stem cells (MSCs) has been considered an effective therapeutic treatment for a variety of diseases including bone fracture. However, there are associated complications along with...

    Authors: Tao Xu, Yongjun Luo, Jiaxing Wang, Ning Zhang, Changjiang Gu, Linwei Li, Dingfei Qian, Weihua Cai, Jin Fan and Guoyong Yin

    Citation: Journal of Nanobiotechnology 2020 18:47

    Content type: Research

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  11. Peripheral nerve injury is one common clinical disease worldwide, in which sciatic nerve is anatomically the most challenging to regenerate given its length and large cross-sectional area. For the present, aut...

    Authors: Zhiwei Fang, Xuemei Ge, Xuan Chen, Yang Xu, Wei-En Yuan and Yuanming Ouyang

    Citation: Journal of Nanobiotechnology 2020 18:46

    Content type: Research

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  12. To effectively applied nanomaterials (NMs) in medicine, one of the top priorities is to address a better understanding of the possible sub-organ transfer, clearance routes, and potential toxicity of the NMs in...

    Authors: Xue Li, Bing Wang, Shuang Zhou, Wei Chen, Hanqing Chen, Shanshan Liang, Lingna Zheng, Hongyang Yu, Runxuan Chu, Meng Wang, Zhifang Chai and Weiyue Feng

    Citation: Journal of Nanobiotechnology 2020 18:45

    Content type: Research

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  13. Traditional sandwich enzyme-linked immunosorbent assay (ELISA) using polyclonal and monoclonal antibodies as reagents presents several drawbacks, including limited amounts, difficulty in permanent storage, and...

    Authors: Pinpin Ji, Jiahong Zhu, Xiaoxuan Li, Wenqi Fan, Qianqian Liu, Kun Wang, Jiakai Zhao, Yani Sun, Baoyuan Liu, En-Min Zhou and Qin Zhao

    Citation: Journal of Nanobiotechnology 2020 18:44

    Content type: Research

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  14. Metastasis causes the most breast cancer-related deaths in women. Here, we investigated the antitumor effect of solid lipid nanoparticles (SLN-DTX) when used in the treatment of metastatic breast tumors using ...

    Authors: Márcia Cristina Oliveira da Rocha, Patrícia Bento da Silva, Marina Arantes Radicchi, Bárbara Yasmin Garcia Andrade, Jaqueline Vaz de Oliveira, Tom Venus, Carolin Merker, Irina Estrela-Lopis, João Paulo Figueiró Longo and Sônia Nair Báo

    Citation: Journal of Nanobiotechnology 2020 18:43

    Content type: Research

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  15. Identifying the precise location of cells and their migration dynamics is of utmost importance for achieving the therapeutic potential of cells after implantation into a host. Magnetic resonance imaging is a s...

    Authors: Aldo Isaac Martínez-Banderas, Antonio Aires, Sandra Plaza-García, Lorena Colás, Julián A. Moreno, Timothy Ravasi, Jasmeen S. Merzaban, Pedro Ramos-Cabrer, Aitziber L. Cortajarena and Jürgen Kosel

    Citation: Journal of Nanobiotechnology 2020 18:42

    Content type: Research

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  16. The identification of foodborne pathogenic bacteria types plays a crucial role in food safety and public health. In consideration of long culturing times, tedious operations and the desired specific recognitio...

    Authors: Mingyuan Yin, Chuang Jing, Haijie Li, Qiliang Deng and Shuo Wang

    Citation: Journal of Nanobiotechnology 2020 18:41

    Content type: Research

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  17. The repair of large bone defects is a great challenge in clinical practice. In this study, copper-loaded-ZIF-8 nanoparticles and poly (lactide-co-glycolide) (PLGA) were combined to fabricate porous PLGA/Cu(I)@ZIF...

    Authors: Fei Zou, Jianyuan Jiang, Feizhou Lv, Xinlei Xia and Xiaosheng Ma

    Citation: Journal of Nanobiotechnology 2020 18:39

    Content type: Research

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  18. Macrophage polarization and reprogramming in the lung play a critical role in the initiation, development and progression of acute lung injury (ALI). Regulating the activation and differentiation of pulmonary ...

    Authors: Lu Wang, Huasheng Zhang, Liya Sun, Wei Gao, Ye Xiong, Aying Ma, Xiali Liu, Lei Shen, Qiang Li and Hong Yang

    Citation: Journal of Nanobiotechnology 2020 18:38

    Content type: Research

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  19. Functionalized multi-walled carbon nanotubes (MWCNT) have become the focus of increased research interest, particularly in their application as tools in different areas, such as the biomedical field. Despite t...

    Authors: Sara Nahle, Hilary Cassidy, Mélanie M. Leroux, Reuben Mercier, Jaafar Ghanbaja, Zahra Doumandji, David Matallanas, Bertrand H. Rihn, Olivier Joubert and Luc Ferrari

    Citation: Journal of Nanobiotechnology 2020 18:36

    Content type: Research

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  20. Novel methods are necessary to reduce morbidity and mortality of patients suffering from infections with Pseudomonas aeruginosa. Being the most common infectious species of the Pseudomonas genus, P. aeruginosa is...

    Authors: Leisha M. Armijo, Stephen J. Wawrzyniec, Michael Kopciuch, Yekaterina I. Brandt, Antonio C. Rivera, Nathan J. Withers, Nathaniel C. Cook, Dale L. Huber, Todd C. Monson, Hugh D. C. Smyth and Marek Osiński

    Citation: Journal of Nanobiotechnology 2020 18:35

    Content type: Research

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  21. The polymer-based drug/gene delivery is promising for the treatment of inherent or acquire disease, because of the polymer’s structural flexibility, larger capacity for therapeutic agent, low host immunogenici...

    Authors: Mingxing Wang, Bo Wu, Jason D. Tucker, Sapana N. Shah, Peijuan Lu and Qilong Lu

    Citation: Journal of Nanobiotechnology 2020 18:34

    Content type: Research

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  22. Prevalence of osteoporosis is rapidly growing and so searching for novel therapeutics. Yet, there is no drug on the market available to modulate osteoclasts and osteoblasts activity simultaneously. Thus in pre...

    Authors: K. Marycz, P. Sobierajska, M. Roecken, K. Kornicka-Garbowska, M. Kępska, R. Idczak, J.-M. Nedelec and R. J. Wiglusz

    Citation: Journal of Nanobiotechnology 2020 18:33

    Content type: Research

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  23. Gold nanoparticles (GNPs) are one of the most widely used nanomaterials in various fields. Especially, the unique chemical and physical properties make them as the promising candidates in drug target identific...

    Authors: Xiao Tu, Xiaoping Tan, Xiaozhou Qi, Aiguo Huang, Fei Ling and Gaoxue Wang

    Citation: Journal of Nanobiotechnology 2020 18:32

    Content type: Research

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  24. Myeloid derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) are two of the major players involved in the inhibition of anti-tumor immune response in cancer patients, leading to poor progno...

    Authors: Laura Pinton, Sara Magri, Elena Masetto, Marina Vettore, Ilaria Schibuola, Vincenzo Ingangi, Ilaria Marigo, Kevin Matha, Jean-Pierre Benoit, Alessandro Della Puppa, Vincenzo Bronte, Giovanna Lollo and Susanna Mandruzzato

    Citation: Journal of Nanobiotechnology 2020 18:31

    Content type: Research

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  25. The surface of a nanoparticle adsorbs molecules from its surroundings with a specific affinity determined by the chemical and physical properties of the nanomaterial. When a nanoparticle is exposed to a biolog...

    Authors: Jasmina Kurepa, Timothy E. Shull and Jan A. Smalle

    Citation: Journal of Nanobiotechnology 2020 18:28

    Content type: Research

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  26. Neural interfaces often elicit inflammatory responses and neuronal loss in the surrounding tissue which adversely affect the function and longevity of the implanted device. Minocycline, an anti-inflammatory ph...

    Authors: Alexander Dontsios Holmkvist, Johan Agorelius, Matilde Forni, Ulf J. Nilsson, Cecilia Eriksson Linsmeier and Jens Schouenborg

    Citation: Journal of Nanobiotechnology 2020 18:27

    Content type: Research

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  27. Gene therapy remains a significant challenge due to lots of barriers limiting the genetic manipulation technologies. As for non-viral delivery vectors, they often suffer insufficient performance due to inadequ...

    Authors: Xi-Xi Ma, Jing-Liang Xu, Yi-Yang Jia, Ya-Xuan Zhang, Wei Wang, Chen Li, Wei He, Si-Yuan Zhou and Bang-Le Zhang

    Citation: Journal of Nanobiotechnology 2020 18:26

    Content type: Research

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  28. Oleic acid (OA) is reported to show anti-inflammatory activity toward activated neutrophils. It is also an important material in nanoparticles for increased stability and cellular internalization. We aimed to ...

    Authors: Huang-Ping Yu, Fu-Chao Liu, Ani Umoro, Zih-Chan Lin, Ahmed O. Elzoghby, Tsong-Long Hwang and Jia-You Fang

    Citation: Journal of Nanobiotechnology 2020 18:25

    Content type: Research

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  29. Targeted delivery of virus-associated antigens to professional antigen-presenting cells (APCs) is considered as an efficient strategy to enhance the pyrophytic effect of vaccines against rhabdovirus disease.

    Authors: Chen Zhang, Gao-Xue Wang and Bin Zhu

    Citation: Journal of Nanobiotechnology 2020 18:24

    Content type: Research

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  31. Superparamagnetic iron oxide nanoparticles (SPION) are extensively used for magnetic resonance imaging (MRI) and magnetic particle imaging (MPI), as well as for magnetic fluid hyperthermia (MFH). We here descr...

    Authors: Seyed Mohammadali Dadfar, Denise Camozzi, Milita Darguzyte, Karolin Roemhild, Paola Varvarà, Josbert Metselaar, Srinivas Banala, Marcel Straub, Nihan Güvener, Ulrich Engelmann, Ioana Slabu, Miriam Buhl, Jan van Leusen, Paul Kögerler, Benita Hermanns-Sachweh, Volkmar Schulz…

    Citation: Journal of Nanobiotechnology 2020 18:22

    Content type: Research

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  32. Carbon nanoparticles (CNPs) have been reported to boost plant growth, while the mechanism that CNPs enhanced potassium uptake for plant growth has not been reported so far.

    Authors: Lijuan Chen, Jinchu Yang, Xiang Li, Taibo Liang, Cong Nie, Fuwei Xie, Kejian Liu, Xiaojun Peng and Jianping Xie

    Citation: Journal of Nanobiotechnology 2020 18:21

    Content type: Research

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  33. Extracellular vesicles (EVs) have shown great potential for targeted therapy, as they have a natural ability to pass through biological barriers and, depending on their origin, can preferentially accumulate at...

    Authors: Pablo Lara, Sujey Palma-Florez, Edison Salas-Huenuleo, Iva Polakovicova, Simón Guerrero, Lorena Lobos-Gonzalez, America Campos, Luis Muñoz, Carla Jorquera-Cordero, Manuel Varas-Godoy, Jorge Cancino, Eloísa Arias, Jaime Villegas, Luis J. Cruz, Fernando Albericio, Eyleen Araya…

    Citation: Journal of Nanobiotechnology 2020 18:20

    Content type: Research

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  34. Biodistribution of photosensitizer (PS) in photodynamic therapy (PDT) can be assessed by fluorescence imaging that visualizes the accumulation of PS in malignant tissue prior to PDT. At the same time, excitati...

    Authors: O. M. Chepurna, A. Yakovliev, R. Ziniuk, O. A. Nikolaeva, S. M. Levchenko, H. Xu, M. Y. Losytskyy, J. L. Bricks, Yu. L. Slominskii, L. O. Vretik, J. Qu and T. Y. Ohulchanskyy

    Citation: Journal of Nanobiotechnology 2020 18:19

    Content type: Research

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  35. Although accumulating evidence suggests that the crosstalk between malignant cells and cancer-associated fibroblasts (CAFs) actively contributes to tumour growth and metastatic dissemination, therapeutic strat...

    Authors: Dávid Kovács, Nóra Igaz, Annamária Marton, Andrea Rónavári, Péter Bélteky, László Bodai, Gabriella Spengler, László Tiszlavicz, Zsolt Rázga, Péter Hegyi, Csaba Vizler, Imre M. Boros, Zoltán Kónya and Mónika Kiricsi

    Citation: Journal of Nanobiotechnology 2020 18:18

    Content type: Research

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  36. This study aimed to develop a new colon-targeted drug delivery system via the preparation of ternary nanocomposite carriers based on organic polymer, aminoclay and lipid vesicles. Budesonide (Bud), an anti-inf...

    Authors: Hyeon Young Kim, Jae Hee Cheon, Sang Hoon Lee, Jeong Youn Min, Seung-Yun Back, Jae Geun Song, Da Hye Kim, Soo-Jeong Lim and Hyo-Kyung Han

    Citation: Journal of Nanobiotechnology 2020 18:17

    Content type: Research

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  37. The clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9 protein system is a revolutionary tool for gene therapy. Despite promising reports of the utility of CRISPR–Cas9 for in vivo gene...

    Authors: Ami Jo, Veronica M. Ringel-Scaia, Dylan K. McDaniel, Cassidy A. Thomas, Rui Zhang, Judy S. Riffle, Irving C. Allen and Richey M. Davis

    Citation: Journal of Nanobiotechnology 2020 18:16

    Content type: Research

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  38. The successful deliveries of siRNA depend on their stabilities under physiological conditions because greater in vivo stability enhances cellular uptake and enables endosomal escape. Viral-based systems appear...

    Authors: Aena Yi, Dahye Sim, Young-Jin Lee, Vijaya Sarangthem and Rang-Woon Park

    Citation: Journal of Nanobiotechnology 2020 18:15

    Content type: Research

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  39. In orthopedics, the treatment of implant-associated infections represents a high challenge. Especially, potent antibacterial effects at implant surfaces can only be achieved by the use of high doses of antibio...

    Authors: Hilke Catherina Janßen, Nina Angrisani, Stefan Kalies, Florian Hansmann, Manfred Kietzmann, Dawid Peter Warwas, Peter Behrens and Janin Reifenrath

    Citation: Journal of Nanobiotechnology 2020 18:14

    Content type: Research

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  40. During the past few decades, drug delivery system (DDS) has attracted many interests because it could enhance the therapeutic effects of drugs and reduce their side effects. The advent of nanotechnology has pr...

    Authors: Ming Gao, Yifeng Yang, Andreas Bergfel, Lanli Huang, Li Zheng and Tim Melander Bowden

    Citation: Journal of Nanobiotechnology 2020 18:13

    Content type: Research

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  41. CD47, the integrin-related protein, plays an important role in immune resistance and escape of tumor cells. Antibodies blocking the CD47/SIRPα signal pathway can effectively stimulate macrophage-mediated phago...

    Authors: Linlin Ma, Min Zhu, Junwei Gai, Guanghui Li, Qing Chang, Peng Qiao, Longlong Cao, Wanqing Chen, Siyuan Zhang and Yakun Wan

    Citation: Journal of Nanobiotechnology 2020 18:12

    Content type: Research

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  42. In several years ago, infection with human papillomaviruses (HPVs), have been prevalent in the worlds especially HPV type 18, can lead to cervical cancer. Therefore, rapid, accurate, and early diagnosis of HPV...

    Authors: Pegah Mahmoodi, Majid Rezayi, Elisa Rasouli, Amir Avan, Mehrdad Gholami, Majid Ghayour Mobarhan, Ehsan Karimi and Yatima Alias

    Citation: Journal of Nanobiotechnology 2020 18:11

    Content type: Research

    Published on:

  43. 5-Fluorouracil (5-FU) has been commonly prescribed for patients with colorectal cancer (CRC), but resistance to 5-FU is one of the main reasons for failure in CRC. Recently, microRNAs (miRNAs) have been establ...

    Authors: Gaofeng Liang, Yanliang Zhu, Doulathunnisa Jaffar Ali, Tian Tian, Huantian Xu, Ke Si, Bo Sun, Baoan Chen and Zhongdang Xiao

    Citation: Journal of Nanobiotechnology 2020 18:10

    Content type: Research

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  44. The vascular system, which transports oxygen and nutrients, plays an important role in wound healing, cardiovascular disease treatment and bone tissue engineering. Angiogenesis is a complex and delicate regula...

    Authors: Wenjing Liu, Guilan Zhang, Junrong Wu, Yanli Zhang, Jia Liu, Haiyun Luo and Longquan Shao

    Citation: Journal of Nanobiotechnology 2020 18:9

    Content type: Review

    Published on:

  45. Chemotherapeutic drugs frequently encounter multidrug resistance. ATP from mitochondria helps overexpression of drug efflux pumps to induce multidrug resistance, so mitochondrial delivery as a means of “repurp...

    Authors: He Wang, Fangke Zhang, Huaying Wen, Wenwen Shi, Qiudi Huang, Yugang Huang, Jiacui Xie, Peiyin Li, Jianhai Chen, Linghao Qin and Yi Zhou

    Citation: Journal of Nanobiotechnology 2020 18:8

    Content type: Research

    Published on:

  46. Antibodies are an important reagent to determine the specificity and accuracy of diagnostic immunoassays for various diseases. However, traditional antibodies have several shortcomings due to their limited abu...

    Authors: Qizhong Lu, Xiaoxuan Li, Jiakai Zhao, Jiahong Zhu, Yuhang Luo, Hong Duan, Pinpin Ji, Kun Wang, Baoyuan Liu, Xueting Wang, Wenqi Fan, Yani Sun, En-Min Zhou and Qin Zhao

    Citation: Journal of Nanobiotechnology 2020 18:7

    Content type: Research

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  47. Haptoglobin is an acute-phase protein used as predicting diagnostic biomarker both in humans (i.e., diabetes, ovarian cancer, some neurological and cardiovascular disorders) and in animals (e.g., bovine mastit...

    Authors: Narsingh R. Nirala, Yifat Harel, Jean-Paul Lellouche and Giorgi Shtenberg

    Citation: Journal of Nanobiotechnology 2020 18:6

    Content type: Research

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  48. Lipid nanocapsules (LNCs) are promising vehicles for drug delivery. However, since not much was known about cellular toxicity of these nanoparticles in themselves, we have here investigated the mechanisms invo...

    Authors: Marzena Szwed, Maria Lyngaas Torgersen, Remya Valsala Kumari, Sunil Kumar Yadava, Sascha Pust, Tore Geir Iversen, Tore Skotland, Jyotsnendu Giri and Kirsten Sandvig

    Citation: Journal of Nanobiotechnology 2020 18:5

    Content type: Research

    Published on:

  49. Disulfiram (DSF) has been considered as “Repurposing drug” in cancer therapy in recent years based on its good antitumor efficacy. DSF is traditionally used as an oral drug in the treatment of alcoholism. To o...

    Authors: Haowen Li, Biao Liu, Hui Ao, Jingxin Fu, Yian Wang, Yue Feng, Yifei Guo and Xiangtao Wang

    Citation: Journal of Nanobiotechnology 2020 18:4

    Content type: Research

    Published on:

  50. After publication of this article, an error was found in the description of the holmium isotopes. 165Ho is a stable isotope a fraction of which is activated to 166Ho by neutron activation in a nuclear reactor [2]...

    Authors: Oleksii O. Peltek, Albert R. Muslimov, Mikhail V. Zyuzin and Alexander S. Timin

    Citation: Journal of Nanobiotechnology 2020 18:2

    Content type: Correction

    Published on:

    The original article was published in Journal of Nanobiotechnology 2019 17:90

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Journal of Nanobiotechnology

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