Table 1 Encapsulation efficiencies applying different PLGAs and preparation techniques
Applied technique | Copolymer ration of PLGA | Protein concentration (mg/ml) | Encapsulation yield |
|---|---|---|---|
Double emulsion technique | 75:25 | 0.39 | % 92.2 ± 5.5 |
Double emulsion technique | 50:50 | 0.27 | % 94.6 ± 5.5 |
Nonaqueous emulsion technique | 50:50 | 0.6 | % 88 ± 5.5 |