Figure 4
From: Magnetic core-shell nanoparticles for drug delivery by nebulization
In vivo biocompatibility analysis of MNPs. A. Measurement of total glutathione levels in lung tissue from mice treated with a single intranasal delivery. Lungs were harvested from treated mice at 1, 4 and 7 days post-treatment with uncoated MNP, PLGA-MNP or LPS (used as a positive control). B. Measurement of IL-6 levels in BAL fluid from mice treated with a single intranasal delivery. BAL fluid was obtained from treated mice at 1, 4 and 7 days post-treatment with MNP, PLGA-MNP or LPS. Data are mean ± SEM of at least 3 animals under each treatment conditions.