Table 2 GLA concentration of buffered GLA-AF compositions
Aqueous phase compositions and concentrations (mM) | Measured GLA concentration (μg/ml) [1000 ± 200 μg/ml target) | |
|---|---|---|
DM | 6 mo | |
Ammonium phosphate (5) | 737 ± 34 | 715 ± 34 |
Ammonium phosphate (12.5) Lot 1 | 861 ± 21 | 791 ± 21 |
Ammonium phosphate (12.5) Lot 2 | 860 ± 24 | N/A |
Ammonium phosphate (20) | 920 ± 13 | N/A |
Ammonium phosphate (25) | 982 ± 15 | N/A |
Citric acid (10) | 886 ± 14 | N/A |
Phosphate buffered saline (50), pH 6.1 | 960 ± 18 | N/A |
HEPES (10) | 945 ± 25 | 912 ± 28 |
Water Lot 1 | 864 ± 28 | 992 ± 8 |
Water Lot 2 | 930 ± 14 | 773 ± 6 |