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Figure 3 | Journal of Nanobiotechnology

Figure 3

From: Entrapment of an EGFR inhibitor into nanostructured lipid carriers (NLC) improves its antitumor activity against human hepatocarcinoma cells

Figure 3

A) Expression of EGFR in human hepatocellular carcinoma HA22T/VGH cells. B) Effects of free tyrphostin AG-1478, empty-NLC and tyrphostin AG-1478-loaded NLC on the ability of human hepatocellular carcinoma cell line HA22T/VGH to form colony. Cells were plated overnight and exposed to the indicated concentration of solvent (DMSO), free tyrphostin, empty-NLC and tyrphostin-loaded NLC for 24 hours followed by growth in fresh culture media for 8 days, as described in Materials and Methods. Surviving colonies were stained (upper panel) and counted (lower panel). Data are expressed as a percentage of colony in untreated cells and are the mean ± SD of two determinations.

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Journal of Nanobiotechnology

ISSN: 1477-3155

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